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CALCOCO2 抗体 (AA 137-446)

CALCOCO2 适用: 人 WB, ELISA, IHC, IP 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7146349
发货至: 中国
  • 抗原 See all CALCOCO2 抗体
    CALCOCO2 (Calcium Binding and Coiled-Coil Domain 2 (CALCOCO2))
    抗原表位
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 137-446
    适用
    • 28
    • 5
    • 3
    • 1
    • 1
    宿主
    • 18
    • 11
    克隆类型
    • 20
    • 9
    多克隆
    标记
    • 22
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CALCOCO2 antibody is un-conjugated
    应用范围
    • 22
    • 11
    • 5
    • 5
    • 4
    • 4
    • 3
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)
    交叉反应
    纯化方法
    Antigen Affinity Purified
    免疫原
    Recombinant Human Calcium-binding and coiled-coil domain-containing protein 2 protein (137-446AA)
    亚型
    IgG
  • 应用备注
    Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200, IP:1:200-1:2000,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    CALCOCO2 (Calcium Binding and Coiled-Coil Domain 2 (CALCOCO2))
    别名
    CALCOCO2 (CALCOCO2 产品)
    别名
    CALCOCO2 antibody, MGC110205 antibody, wu:fj08c01 antibody, zgc:110205 antibody, DKFZp469D2219 antibody, NDP52 antibody, 2410154J16Rik antibody, C77254 antibody, Ndp52 antibody, Ndp52l1 antibody, RGD1559974 antibody, calcium binding and coiled-coil domain 2 antibody, CALCOCO2 antibody, calcoco2 antibody, Calcoco2 antibody
    背景

    Background: Xenophagy-specific receptor required for autophagy-mediated intracellular bacteria degradation. Acts as an effector protein of galectin-sensed membrane damage that restricts the proliferation of infecting pathogens such as Salmonella typhimurium upon entry into the cytosol by targeting galectin-8-associated bacteria for autophagy (PubMed:22246324). Initially orchestrates bacteria targeting to autophagosomes and subsequently ensures pathogen degradation by regulating pathogen-containing autophagosome maturation (PubMed:23022382, PubMed:25771791). Bacteria targeting to autophagosomes relies on its interaction with MAP1LC3A, MAP1LC3B and/or GABARAPL2, whereas regulation of pathogen-containing autophagosome maturation requires the interaction with MAP3LC3C (PubMed:23022382, PubMed:25771791). May play a role in ruffle formation and actin cytoskeleton organization and seems to negatively regulate constitutive secretion (PubMed:17635994).

    Aliases: Antigen nuclear dot 52 kDa protein antibody, CACO2_HUMAN antibody, Calcium binding and coiled coil domain 2 antibody, Calcium binding and coiled coil domain containing protein 2 antibody, Calcium-binding and coiled-coil domain-containing protein 2 antibody, CALCOCO 2 antibody, CALCOCO2 antibody, MGC17318 antibody, NDP52 antibody, Nuclear domain 10 protein 52 antibody, Nuclear domain 10 protein antibody, Nuclear domain 10 protein NDP52 antibody, Nuclear domain protein 52 antibody, Nuclear dot protein 52 antibody, OTTHUMP00000218344 antibody, OTTHUMP00000218345 antibody, OTTHUMP00000218346 antibody, OTTHUMP00000218347 antibody, OTTHUMP00000218349 antibody, OTTHUMP00000218351 antibody

    UniProt
    Q13137
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