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- 抗原 See all EFHA1 抗体
- EFHA1 (EF-Hand Domain Family, Member A1 (EFHA1))
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抗原表位
- AA 26-247
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This EFHA1 antibody is un-conjugated
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应用范围
- ELISA, Immunohistochemistry (IHC)
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human Calcium uptake protein 2, mitochondrial protein (26-247AA)
- 亚型
- IgG
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anti-EF-Hand Domain Family, Member A1 (EFHA1) (AA 1-434) antibody
EFHA1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-EF-Hand Domain Family, Member A1 (EFHA1) (AA 50-150) antibodyEFHA1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Recommended dilution: IHC:1:20-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- EFHA1 (EF-Hand Domain Family, Member A1 (EFHA1))
- 别名
- MICU2 (EFHA1 产品)
- 别名
- 1110008L20Rik antibody, EFHA1 antibody, Efha1 antibody, RGD1309934 antibody, Smhs2 antibody, 4833427E09Rik antibody, AU041871 antibody, mitochondrial calcium uptake 2 antibody, MICU2 antibody, Micu2 antibody
- 背景
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Background: Key regulator of mitochondrial calcium uniporter (MCU) required to limit calcium uptake by MCU when cytoplasmic calcium is low (PubMed:24503055, PubMed:24560927, PubMed:26903221). MICU1 and MICU2 form a disulfide-linked heterodimer that stimulate and inhibit MCU activity, depending on the concentration of calcium (PubMed:24560927). MICU2 acts as a gatekeeper of MCU that senses calcium level via its EF-hand domains: prevents channel opening at resting calcium, avoiding energy dissipation and cell-death triggering (PubMed:24560927).
Aliases: 1110008L20Rik antibody, EF hand domain containing family member A1 antibody, EF hand domain family A1 antibody, EF hand domain family member A1 antibody, EF-hand domain-containing family member A1 antibody, EFHA1 antibody, EFHA1 EF hand domain family member A1 antibody, EFHA1_HUMAN antibody, FLJ25016 antibody, FLJ34588 antibody, Smhs2 homolog antibody
- UniProt
- Q8IYU8
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