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KCTD6 抗体 (AA 1-237) (HRP)

KCTD6 适用: 人 ELISA 宿主: 兔 Polyclonal HRP
产品编号 ABIN7145859
发货至: 中国
  • 抗原 See all KCTD6 抗体
    KCTD6 (Potassium Channel Tetramerisation Domain Containing 6 (KCTD6))
    抗原表位
    • 7
    • 7
    • 6
    • 6
    • 6
    • 4
    • 1
    • 1
    • 1
    AA 1-237
    适用
    • 27
    • 13
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    宿主
    • 25
    • 2
    克隆类型
    • 27
    多克隆
    标记
    • 14
    • 4
    • 3
    • 2
    • 2
    • 2
    This KCTD6 antibody is conjugated to HRP
    应用范围
    • 23
    • 16
    • 4
    • 1
    • 1
    ELISA
    交叉反应
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human BTB/POZ domain-containing protein KCTD6 protein (1-237AA)
    亚型
    IgG
    Top Product
    Discover our top product KCTD6 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    KCTD6 (Potassium Channel Tetramerisation Domain Containing 6 (KCTD6))
    别名
    KCTD6 (KCTD6 产品)
    别名
    KCTD6 antibody, 5430433B02Rik antibody, AU044285 antibody, kctd6 antibody, zgc:91884 antibody, KCASH3 antibody, potassium channel tetramerization domain containing 6 antibody, potassium channel tetramerisation domain containing 6 antibody, potassium channel tetramerization domain containing 6b antibody, KCTD6 antibody, kctd6 antibody, Kctd6 antibody, kctd6b antibody
    背景

    Background: Probable substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex mediating the ubiquitination and subsequent proteasomal degradation of target proteins. Promotes the ubiquitination of HDAC1, the function seems to depend on KCTD11:KCTD6 oligomerization. Can function as antagonist of the Hedgehog pathway by affecting the nuclear transfer of transcription factor GLI1, the function probably occurs via HDAC1 down-regulation, keeping GLI1 acetylated and inactive. Inhibits cell growth and tumorigenicity of medulloblastoma (MDB) (PubMed:21472142). Involved in regulating protein levels of ANK1 isoform Mu17 probably implicating CUL3-dependent proteasomal degradation (PubMed:22573887).

    Aliases: BTB/POZ domain-containing protein KCTD6 antibody, KCASH3 antibody, kctd6 antibody, KCTD6_HUMAN antibody, MGC27385 antibody, potassium channel tetramerization domain containing 6 antibody

    UniProt
    Q8NC69
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