电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

BRD8 抗体 (AA 641-859)

BRD8 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7145820
发货至: 中国
  • 抗原 See all BRD8 抗体
    BRD8 (Bromodomain Containing 8 (BRD8))
    抗原表位
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 641-859
    适用
    • 24
    • 10
    • 5
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    宿主
    • 23
    • 2
    克隆类型
    • 23
    • 2
    多克隆
    标记
    • 14
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This BRD8 antibody is un-conjugated
    应用范围
    • 12
    • 7
    • 6
    • 5
    • 5
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    ELISA, Immunohistochemistry (IHC)
    交叉反应
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human Bromodomain-containing protein 8 protein (641-859AA)
    亚型
    IgG
    Top Product
    Discover our top product BRD8 Primary Antibody
  • 应用备注
    Recommended dilution: IHC:1:20-1:200,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    BRD8 (Bromodomain Containing 8 (BRD8))
    别名
    BRD8 (BRD8 产品)
    别名
    SMAP antibody, SMAP2 antibody, p120 antibody, 2610007E11Rik antibody, 4432404P07Rik antibody, bromodomain containing 8 antibody, BRD8 antibody, Brd8 antibody
    背景

    Background: May act as a coactivator during transcriptional activation by hormone-activated nuclear receptors (NR). Isoform 2 stimulates transcriptional activation by AR/DHTR, ESR1/NR3A1, RXRA/NR2B1 and THRB/ERBA2. At least isoform 1 and isoform 2 are components of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when recruited to sites of DNA damage. Component of a SWR1-like complex that specifically mediates the removal of histone H2A.Z/H2AFZ from the nucleosome.

    Aliases: BRD8 antibody, SMAP antibody, SMAP2 antibody, Bromodomain-containing protein 8 antibody, Skeletal muscle abundant protein antibody, Skeletal muscle abundant protein 2 antibody, Thyroid hormone receptor coactivating protein of 120 kDa antibody, TrCP120 antibody, p120 antibody

    UniProt
    Q9H0E9
You are here:
客服