BVES 抗体 (AA 241-360)
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- 抗原 See all BVES 抗体
- BVES (Blood Vessel Epicardial Substance (BVES))
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抗原表位
- AA 241-360
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This BVES antibody is un-conjugated
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应用范围
- ELISA, Immunofluorescence (IF)
- 交叉反应
- 人
- 纯化方法
- Antigen Affinity Purified
- 免疫原
- Recombinant Human Blood vessel epicardial substance protein (241-360AA)
- 亚型
- IgG
- Top Product
- Discover our top product BVES Primary Antibody
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- 应用备注
- Recommended dilution: IF:1:50-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- BVES (Blood Vessel Epicardial Substance (BVES))
- 别名
- BVES (BVES 产品)
- 别名
- HBVES antibody, POP1 antibody, POPDC1 antibody, Pop1 antibody, Popdc1 antibody, mBVES antibody, Popeye-1 antibody, Xbves antibody, Xbves-A antibody, Xpop-1 antibody, Xpop-1-A antibody, pop-1 antibody, pop1 antibody, pop1-A antibody, popdc1 antibody, popdc1-A antibody, zgc:86887 antibody, BVES antibody, Xpop-1-B antibody, bves antibody, pop1-B antibody, popdc1-B antibody, hbves antibody, blood vessel epicardial substance antibody, blood vessel epicardial substance L homeolog antibody, blood vessel epicardial substance S homeolog antibody, BVES antibody, Bves antibody, bves.L antibody, bves antibody, bves.S antibody
- 背景
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Background: Cell adhesion molecule involved in the establishment and/or maintenance of cell integrity. Involved in the formation and regulation of the tight junction (TJ) paracellular permeability barrier in epithelial cells (PubMed:16188940). Plays a role in VAMP3-mediated vesicular transport and recycling of different receptor molecules through its interaction with VAMP3. Plays a role in the regulation of cell shape and movement by modulating the Rho-family GTPase activity through its interaction with ARHGEF25/GEFT. Induces primordial adhesive contact and aggregation of epithelial cells in a Ca(2+)-independent manner. Also involved in striated muscle regeneration and repair and in the regulation of cell spreading (By similarity). Important for the maintenance of cardiac function. Plays a regulatory function in heart rate dynamics mediated, at least in part, through cAMP-binding and, probably, by increasing cell surface expression of the potassium channel KCNK2 and enhancing current density (PubMed:26642364). Is also a caveolae-associated protein important for the preservation of caveolae structural and functional integrity as well as for heart protection against ischemia injury.
Aliases: Blood vessel epicardial substance antibody, Bves antibody, hBVES antibody, MGC42413 antibody, POP 1 antibody, POP1 antibody, POPD1_HUMAN antibody, POPDC 1 antibody, POPDC1 antibody, Popeye domain containing 1 antibody, Popeye domain containing protein 1 antibody, Popeye domain-containing protein 1 antibody, Popeye protein 1 antibody
- UniProt
- Q8NE79
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