JMJD6 抗体 (AA 1-320)
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- 抗原 See all JMJD6 抗体
- JMJD6 (Jumonji Domain Containing 6 (JMJD6))
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抗原表位
- AA 1-320
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This JMJD6 antibody is un-conjugated
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应用范围
- ELISA, Immunohistochemistry (IHC)
- 交叉反应
- 人
- 纯化方法
- Antigen Affinity Purified
- 免疫原
- Recombinant Human Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 protein (1-320AA)
- 亚型
- IgG
- Top Product
- Discover our top product JMJD6 Primary Antibody
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- 应用备注
- Recommended dilution: IHC:1:20-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- JMJD6 (Jumonji Domain Containing 6 (JMJD6))
- 别名
- JMJD6 (JMJD6 产品)
- 别名
- Ptdsr antibody, PSR antibody, PTDSR antibody, PTDSR1 antibody, psr antibody, ptdsr antibody, zfpsr antibody, zgc:66264 antibody, 5730436I23Rik antibody, D11Ertd195e antibody, PtdSerR antibody, mKIAA0585 antibody, GB15204 antibody, jmjd6 antibody, cg5383 antibody, ptdsr1 antibody, arginine demethylase and lysine hydroxylase antibody, jumonji domain containing 6 antibody, bifunctional arginine demethylase and lysyl-hydroxylase PSR antibody, jmjC domain-containing protein 4 homolog antibody, phosphatidylserine receptor antibody, jumonji domain containing 6 S homeolog antibody, jumonji domain containing 6 L homeolog antibody, Jmjd6 antibody, JMJD6 antibody, jmjd6 antibody, LOC411069 antibody, LOC5577546 antibody, CpipJ_CPIJ004848 antibody, CpipJ_CPIJ019866 antibody, jmjd6.S antibody, jmjd6.L antibody
- 背景
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Background: Dioxygenase that can both act as a histone arginine demethylase and a lysyl-hydroxylase. Acts as a lysyl-hydroxylase that catalyzes 5-hydroxylation on specific lysine residues of target proteins such as U2AF2/U2AF65 and LUC7L2. Acts as a regulator of RNA splicing by mediating 5-hydroxylation of U2AF2/U2AF65, affecting the pre-mRNA splicing activity of U2AF2/U2AF65. In addition to peptidyl-lysine 5-dioxygenase activity, may act as an RNA hydroxylase, as suggested by its ability to bind single strand RNA. Also acts as an arginine demethylase which demethylates histone H3 at \\\'Arg-2\\\' (H3R2me) and histone H4 at \\\'Arg-3\\\' (H4R3me), thereby playing a role in histone code. However, histone arginine demethylation may not constitute the primary activity in vivo. Has no histone lysine demethylase activity. Required for differentiation of multiple organs during embryogenesis. Acts as a key regulator of hematopoietic differentiation: required for angiogenic sprouting by regulating the pre-mRNA splicing activity of U2AF2/U2AF65. Seems to be necessary for the regulation of macrophage cytokine responses.
Aliases: Apoptotic cell clearance receptor antibody, Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 antibody, Histone arginine demethylase JMJD6 antibody, JmjC domain-containing protein 6 antibody, JMJD 6 antibody, JMJD6 antibody, JMJD6_HUMAN antibody, Jumonji domain containing 6 antibody, Jumonji domain-containing protein 6 antibody, KIAA0585 antibody, Lysyl-hydroxylase JMJD6 antibody, Peptide-lysine 5-dioxygenase JMJD6 antibody, Phosphatidylserine receptor antibody, Protein PTDSR antibody, PSR antibody, PTDSR 1 antibody, PTDSR antibody, PTDSR1 antibody
- UniProt
- Q6NYC1
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