BNIP3L/NIX 抗体 (AA 1-187)
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- 抗原 See all BNIP3L/NIX (BNIP3L) 抗体
- BNIP3L/NIX (BNIP3L) (BCL2/adenovirus E1B 19kDa Interacting Protein 3-Like (BNIP3L))
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抗原表位
- AA 1-187
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This BNIP3L/NIX antibody is un-conjugated
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应用范围
- Immunohistochemistry (IHC), ELISA
- 交叉反应
- 人
- 纯化方法
- Antigen Affinity Purified
- 免疫原
- Recombinant Human BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like protein (1-187AA)
- 亚型
- IgG
- Top Product
- Discover our top product BNIP3L Primary Antibody
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- 应用备注
- Recommended dilution: IHC:1:20-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- BNIP3L/NIX (BNIP3L) (BCL2/adenovirus E1B 19kDa Interacting Protein 3-Like (BNIP3L))
- 别名
- BNIP3L (BNIP3L 产品)
- 别名
- BNIP3a antibody, NIX antibody, NIP3 antibody, Nix antibody, Nip3 antibody, C86132 antibody, D14Ertd719e antibody, Nip3L antibody, bnip3l antibody, nip3 antibody, zgc:110478 antibody, bnip3l2 antibody, wu:fb52b03 antibody, wu:fc02h04 antibody, BCL2 interacting protein 3 like antibody, BCL2 interacting protein 3 antibody, BCL2/adenovirus E1B interacting protein 3 antibody, BCL2/adenovirus E1B interacting protein 3-like antibody, BCL2/adenovirus E1B interacting protein 3-like b antibody, BCL2/adenovirus E1B interacting protein 3-like a antibody, BNIP3L antibody, BNIP3 antibody, Bnip3l antibody, Bnip3 antibody, bnip3lb antibody, bnip3la antibody
- 背景
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Background: Induces apoptosis. Interacts with viral and cellular anti-apoptosis proteins. Can overcome the suppressors BCL-2 and BCL-XL, although high levels of BCL-XL expression will inhibit apoptosis. Inhibits apoptosis induced by BNIP3. Involved in mitochondrial quality control via its interaction with SPATA18/MIEAP: in response to mitochondrial damage, participates to mitochondrial protein catabolic process (also named MALM) leading to the degradation of damaged proteins inside mitochondria. The physical interaction of SPATA18/MIEAP, BNIP3 and BNIP3L/NIX at the mitochondrial outer membrane regulates the opening of a pore in the mitochondrial double membrane in order to mediate the translocation of lysosomal proteins from the cytoplasm to the mitochondrial matrix. May function as a tumor suppressor.
Aliases: Adenovirus E1B19k binding protein B5 antibody, Adenovirus E1B19K-binding protein B5 antibody, BCL2/adenovirus E1B 19 kd protein interacting protein 3a antibody, BCL2/adenovirus E1B 19 kDa protein interacting protein 3A antibody, BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like antibody, BCL2/adenovirus E1B 19 kDa protein-interacting protein 3A antibody, BCL2/adenovirus E1B 19 kDa interacting protein 3 like antibody, BNI3L_HUMAN antibody, BNIP3a antibody, BNIP3H antibody, BNIP3L antibody, BNIP3L protein antibody, NIP3 like protein X antibody, NIP3-like protein X antibody, NIP3L antibody, NIX antibody
- UniProt
- O60238
- 途径
- Autophagy
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