BNIP3 抗体 (AA 1-164)
-
- 抗原 See all BNIP3 抗体
- BNIP3 (BCL2/adenovirus E1B 19kDa Interacting Protein 3 (BNIP3))
-
抗原表位
- AA 1-164
-
适用
- 人
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This BNIP3 antibody is un-conjugated
-
应用范围
- Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
- 交叉反应
- 人
- 纯化方法
- Antigen Affinity Purified
- 免疫原
- Recombinant Human BCL2/adenovirus E1B 19 kDa protein-interacting protein 3 protein (1-164AA)
- 亚型
- IgG
- Top Product
- Discover our top product BNIP3 Primary Antibody
-
-
- 应用备注
- Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
- 抗原
- BNIP3 (BCL2/adenovirus E1B 19kDa Interacting Protein 3 (BNIP3))
- 别名
- BNIP3 (BNIP3 产品)
- 别名
- NIP3 antibody, Nip3 antibody, BCL2 interacting protein 3 antibody, BCL2/adenovirus E1B interacting protein 3 antibody, BNIP3 antibody, Bnip3 antibody
- 背景
-
Background: Apoptosis-inducing protein that can overcome BCL2 suppression. May play a role in repartitioning calcium between the two major intracellular calcium stores in association with BCL2. Involved in mitochondrial quality control via its interaction with SPATA18/MIEAP: in response to mitochondrial damage, participates to mitochondrial protein catabolic process (also named MALM) leading to the degradation of damaged proteins inside mitochondria. The physical interaction of SPATA18/MIEAP, BNIP3 and BNIP3L/NIX at the mitochondrial outer membrane regulates the opening of a pore in the mitochondrial double membrane in order to mediate the translocation of lysosomal proteins from the cytoplasm to the mitochondrial matrix. Plays an important role in the calprotectin (S100A8/A9)-induced cell death pathway.
Aliases: BCL2 Adenovirus E1B 19 kDa Interacting Protein 3 antibody, BCL2/adenovirus E1B 19 kDa protein interacting protein 3 antibody, BCL2/adenovirus E1B 19 kDa protein-interacting protein 3 antibody, BNIP 3 antibody, BNIP3 antibody, BNIP3_HUMAN antibody, NIP 3 antibody, NIP3 antibody
- UniProt
- Q12983
- 途径
- Autophagy, Brown Fat Cell Differentiation
-