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- 抗原 See all BATF 抗体
- BATF (Basic Leucine Zipper ATF-like Transcription Factor (BATF))
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抗原表位
- AA 1-125
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This BATF antibody is un-conjugated
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应用范围
- ELISA, Western Blotting (WB), Immunohistochemistry (IHC)
- 交叉反应
- 人, 小鼠
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human Basic leucine zipper transcriptional factor ATF-like protein (1-125AA)
- 亚型
- IgG
- Top Product
- Discover our top product BATF Primary Antibody
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anti-Basic Leucine Zipper ATF-like Transcription Factor (BATF) (AA 34-125) antibody
BATF 适用: 人 ELISA, WB, IP 宿主: 小鼠 Monoclonal 8A12 unconjugated
anti-Basic Leucine Zipper ATF-like Transcription Factor (BATF) (AA 34-125) antibodyBATF 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 1G4 unconjugated
anti-Basic Leucine Zipper ATF-like Transcription Factor (BATF) (AA 1-126) antibodyBATF 适用: 人 ELISA 宿主: 小鼠 Monoclonal 7C8F3 unconjugated
anti-Basic Leucine Zipper ATF-like Transcription Factor (BATF) antibodyBATF 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Basic Leucine Zipper ATF-like Transcription Factor (BATF) (AA 34-125) antibodyBATF 适用: 人 ELISA, WB 宿主: 小鼠 Polyclonal unconjugated
anti-Basic Leucine Zipper ATF-like Transcription Factor (BATF) (AA 1-125) antibodyBATF 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Basic Leucine Zipper ATF-like Transcription Factor (BATF) (AA 35-84) antibodyBATF 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 斑马鱼, 猴, Bat, Hamster WB 宿主: 兔 Polyclonal unconjugated
anti-Basic Leucine Zipper ATF-like Transcription Factor (BATF) (N-Term) antibodyBATF 适用: 人, 猴 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- BATF (Basic Leucine Zipper ATF-like Transcription Factor (BATF))
- 别名
- BATF (BATF 产品)
- 别名
- B-ATF antibody, si:ch211-153j24.4 antibody, BATF1 antibody, SFA-2 antibody, SFA2 antibody, basic leucine zipper transcription factor, ATF-like antibody, basic leucine zipper ATF-like transcription factor antibody, batf antibody, BATF antibody, Batf antibody
- 背景
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Background: AP-1 family transcription factor that controls the differentiation of lineage-specific cells in the immune system: specifically mediates the differentiation of T-helper 17 cells (Th17), follicular T-helper cells (TfH), CD8(+) dendritic cells and class-switch recombination (CSR) in B-cells. Acts via the formation of a heterodimer with JUNB that recognizes and binds DNA sequence 5\\\'-TGA[CG]TCA-3\\\'. The BATF-JUNB heterodimer also forms a complex with IRF4 (or IRF8) in immune cells, leading to recognition of AICE sequence (5\\\'-TGAnTCA/GAAA-3\\\'), an immune-specific regulatory element, followed by cooperative binding of BATF and IRF4 (or IRF8) and activation of genes. Controls differentiation of T-helper cells producing interleukin-17 (Th17 cells) by binding to Th17-associated gene promoters: regulates expression of the transcription factor RORC itself and RORC target genes such as IL17 (IL17A or IL17B). Also involved in differentiation of follicular T-helper cells (TfH) by directing expression of BCL6 and MAF. In B-cells, involved in class-switch recombination (CSR) by controlling the expression of both AICDA and of germline transcripts of the intervening heavy-chain region and constant heavy-chain region (I(H)-C(H)). Following infection, can participate in CD8(+) dendritic cell differentiation via interaction with IRF4 and IRF8 to mediate cooperative gene activation. Regulates effector CD8(+) T-cell differentiation by regulating expression of SIRT1. Following DNA damage, part of a differentiation checkpoint that limits self-renewal of hematopoietic stem cells (HSCs): up-regulated by STAT3, leading to differentiation of HSCs, thereby restricting self-renewal of HSCs (By similarity).
Aliases: Activating transcription factor B antibody, B ATF antibody, B-ATF antibody, B-cell-activating transcription factor antibody, Basic leucine zipper transcription factor like antibody, Basic leucine zipper transcriptional factor ATF like antibody, Basic leucine zipper transcriptional factor ATF-like antibody, Batf antibody, BATF_HUMAN antibody, BATF1 antibody, SF HT activated gene 2 protein antibody, SF-HT-activated gene 2 protein antibody, SFA 2 antibody, SFA-2 antibody, SFA2 antibody
- UniProt
- Q16520
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