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BBS2 抗体 (AA 1-96)

BBS2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7145239
发货至: 中国
  • 抗原 See all BBS2 抗体
    BBS2 (Bardet-Biedl Syndrome 2 (BBS2))
    抗原表位
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 1-96
    适用
    • 10
    • 6
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    宿主
    • 8
    • 3
    克隆类型
    • 10
    • 1
    多克隆
    标记
    • 11
    This BBS2 antibody is un-conjugated
    应用范围
    • 11
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    交叉反应
    人, 小鼠
    纯化方法
    Antigen Affinity Purified
    免疫原
    Recombinant Human Bardet-Biedl syndrome 2 protein (1-96AA)
    亚型
    IgG
  • 应用备注
    Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    BBS2 (Bardet-Biedl Syndrome 2 (BBS2))
    别名
    BBS2 (BBS2 产品)
    别名
    fb80a05 antibody, wu:fb80a05 antibody, DKFZp468B105 antibody, DKFZp469L0919 antibody, BBS antibody, 2410125H22Rik antibody, AI447581 antibody, Bardet-Biedl syndrome 2 antibody, bardet-biedl syndrome 2 antibody, Bardet-Biedl syndrome 2 (human) antibody, bbs2 antibody, BBS2 antibody, Bbs2 antibody
    背景

    Background: The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8, the guanosyl exchange factor (GEF) for Rab8 and then the Rab8-GTP localizes to the cilium and promotes docking and fusion of carrier vesicles to the base of the ciliary membrane. The BBSome complex, together with the LTZL1, controls SMO ciliary trafficking and contributes to the sonic hedgehog (SHH) pathway regulation. Required for proper BBSome complex assembly and its ciliary localization.

    Aliases: BBS2Bardet-Biedl syndrome 2 protein antibody

    UniProt
    Q9BXC9
    途径
    Hedgehog Signaling
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