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- 抗原 See all BIRC7 抗体
- BIRC7 (Baculoviral IAP Repeat-Containing 7 (BIRC7))
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抗原表位
- AA 1-265
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This BIRC7 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 交叉反应
- 人
- 纯化方法
- Antigen Affinity Purified
- 免疫原
- Recombinant Human Baculoviral IAP repeat-containing protein 7 protein (1-265AA)
- 亚型
- IgG
- Top Product
- Discover our top product BIRC7 Primary Antibody
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anti-Baculoviral IAP Repeat-Containing 7 (BIRC7) (AA 101-200) antibody
BIRC7 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Baculoviral IAP Repeat-Containing 7 (BIRC7) antibodyBIRC7 适用: 人 WB, IHC (p), IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Baculoviral IAP Repeat-Containing 7 (BIRC7) (AA 1-90) antibodyBIRC7 适用: 人 ELISA, IF 宿主: 小鼠 Monoclonal 3H1 unconjugated
anti-Baculoviral IAP Repeat-Containing 7 (BIRC7) (AA 264-280) antibodyBIRC7 适用: 人, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Baculoviral IAP Repeat-Containing 7 (BIRC7) (C-Term) antibodyVerified BIRC7 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Baculoviral IAP Repeat-Containing 7 (BIRC7) (AA 87-298) antibodyBIRC7 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Baculoviral IAP Repeat-Containing 7 (BIRC7) antibodyBIRC7 适用: 人 WB, IF, FACS 宿主: 小鼠 Monoclonal 1B10 unconjugated
anti-Baculoviral IAP Repeat-Containing 7 (BIRC7) (C-Term) antibodyBIRC7 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Baculoviral IAP Repeat-Containing 7 (BIRC7) (N-Term) antibodyBIRC7 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Baculoviral IAP Repeat-Containing 7 (BIRC7) (AA 1-298) antibodyBIRC7 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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- 应用备注
- Recommended dilution: WB:1:200-1:1000,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- BIRC7 (Baculoviral IAP Repeat-Containing 7 (BIRC7))
- 别名
- BIRC7 (BIRC7 产品)
- 别名
- KIAP antibody, LIVIN antibody, ML-IAP antibody, MLIAP antibody, RNF50 antibody, EIAP/XLX antibody, XLX antibody, kiap antibody, livin antibody, ml-iap antibody, mliap antibody, rnf50 antibody, xEIAP antibody, RGD1562883 antibody, zgc:165605 antibody, E130019N06 antibody, Livin antibody, birc7 antibody, bird7a antibody, xEIAP/XLX antibody, xlx antibody, EIAP/XLX-B antibody, birc7b antibody, baculoviral IAP repeat containing 7 antibody, baculoviral IAP repeat-containing 7 antibody, baculoviral IAP repeat-containing 7 (livin) antibody, baculoviral IAP repeat containing 7 S homeolog antibody, baculoviral IAP repeat containing 7 L homeolog antibody, BIRC7 antibody, birc7 antibody, Birc7 antibody, birc7.S antibody, birc7.L antibody
- 背景
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Background: Apoptotic regulator capable of exerting proapoptotic and anti-apoptotic activities and plays crucial roles in apoptosis, cell proliferation, and cell cycle control. Its anti-apoptotic activity is mediated through the inhibition of CASP3, CASP7 and CASP9, as well as by its E3 ubiquitin-protein ligase activity. As it is a weak caspase inhibitor, its anti-apoptotic activity is thought to be due to its ability to ubiquitinate DIABLO/SMAC targeting it for degradation thereby promoting cell survival. May contribute to caspase inhibition, by blocking the ability of DIABLO/SMAC to disrupt XIAP/BIRC4-caspase interactions. Protects against apoptosis induced by TNF or by chemical agents such as adriamycin, etoposide or staurosporine. Suppression of apoptosis is mediated by activation of MAPK8/JNK1, and possibly also of MAPK9/JNK2. This activation depends on TAB1 and NR2C2/TAK1. In vitro, inhibits CASP3 and proteolytic activation of pro-CASP9. Isoform 1 blocks staurosporine-induced apoptosis. Isoform 2 blocks etoposide-induced apoptosis. Isoform 2 protects against natural killer (NK) cell killing whereas isoform 1 augments killing.
Aliases: Baculoviral IAP repeat containing 7 antibody, Baculoviral IAP repeat containing protein 7 antibody, Baculoviral IAP repeat-containing protein 7 antibody, BIRC 7 antibody, birc7 antibody, BIRC7_HUMAN antibody, KIAP antibody, Kidney inhibitor of apoptosis protein antibody, Livin antibody, Livin inhibitor of apotosis antibody, Melanoma inhibitor of apoptosis protein antibody, ML IAP antibody, ML-IAP antibody, MLIAP antibody, RING finger protein 50 antibody, RNF 50 antibody, RNF50 antibody
- UniProt
- Q96CA5
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