CD79a 抗体 (AA 70-142)
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- 抗原 See all CD79a (CD79A) 抗体
- CD79a (CD79A) (B-cell antigen receptor complex-associated protein alpha chain (CD79A))
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抗原表位
- AA 70-142
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CD79a antibody is un-conjugated
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应用范围
- Immunofluorescence (IF), Immunohistochemistry (IHC), ELISA
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human B-cell antigen receptor complex-associated protein alpha chain protein (70-142AA)
- 亚型
- IgG
- Top Product
- Discover our top product CD79A Primary Antibody
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- 应用备注
- Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- CD79a (CD79A) (B-cell antigen receptor complex-associated protein alpha chain (CD79A))
- 别名
- CD79A (CD79A 产品)
- 别名
- CD79A antibody, Ig-alpha antibody, Iga antibody, Igalpha antibody, Ly-54 antibody, Ly54 antibody, mb-1 antibody, IGA antibody, MB-1 antibody, IG-alpha antibody, CD79a molecule antibody, CD79A antigen (immunoglobulin-associated alpha) antibody, Cd79a molecule-like antibody, CD79A antibody, Cd79a antibody, Cd79al antibody
- 背景
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Background: Required in cooperation with CD79B for initiation of the signal transduction cascade activated by binding of antigen to the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Also required for BCR surface expression and for efficient differentiation of pro- and pre-B-cells. Stimulates SYK autophosphorylation and activation. Binds to BLNK, bringing BLNK into proximity with SYK and allowing SYK to phosphorylate BLNK. Also interacts with and increases activity of some Src-family tyrosine kinases. Represses BCR signaling during development of immature B-cells.
Aliases: B lymphocyte-specific MB1 protein antibody, B-cell antigen receptor complex-associated protein alpha chain antibody, CD 79a antibody, CD79a antibody, CD79a antigen (immunoglobulin-associated alpha) antibody, CD79A antigen antibody, CD79a molecule, immunoglobulin-associated alpha antibody, CD79A_HUMAN antibody, Ig alpha antibody, Ig-alpha antibody, IGA antibody, IgM-alpha antibody, Immunoglobulin-associated alpha antibody, Ly54 antibody, MB-1 membrane glycoprotein antibody, MB1 antibody, Membrane-bound immunoglobulin-associated protein antibody, Surface IgM-associated protein antibody
- UniProt
- P11912
- 途径
- BCR Signaling
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