-
- 抗原 See all AIRE 抗体
- AIRE (Autoimmune Regulator (AIRE))
-
抗原表位
- AA 39-108
-
适用
- 人
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This AIRE antibody is un-conjugated
-
应用范围
- ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC)
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human Autoimmune regulator protein (39-108AA)
- 亚型
- IgG
- Top Product
- Discover our top product AIRE Primary Antibody
-
anti-Autoimmune Regulator (AIRE) (C-Term) antibody
Verified AIRE 适用: 人 WB, ELISA, IF, IHC, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Autoimmune Regulator (AIRE) (AA 30-130) antibodyAIRE 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Autoimmune Regulator (AIRE) (N-Term) antibodyAIRE 适用: 人, 小鼠, 大鼠, 犬, 马, Cow, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Autoimmune Regulator (AIRE) (Internal Region) antibodyAIRE 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Autoimmune Regulator (AIRE) (Internal Region) antibodyVerified AIRE 适用: 人, Pig WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Autoimmune Regulator (AIRE) (pSer156) antibodyAIRE 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Autoimmune Regulator (AIRE) (AA 467-516) antibodyAIRE 适用: 人, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Autoimmune Regulator (AIRE) (AA 218-267) antibodyAIRE 适用: 人, 马, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Autoimmune Regulator (AIRE) antibodyAIRE 适用: 人, 小鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-Autoimmune Regulator (AIRE) (Internal Region) antibodyAIRE 适用: 人, 小鼠 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
-
- 应用备注
- Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 缓冲液
-
Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
- 抗原
- AIRE (Autoimmune Regulator (AIRE))
- 别名
- AIRE (AIRE 产品)
- 别名
- AIRE1 antibody, APECED antibody, APS1 antibody, APSI antibody, PGA1 antibody, autoimmune regulator antibody, autoimmune regulator (autoimmune polyendocrinopathy candidiasis ectodermal dystrophy) antibody, AaeL_AAEL013794 antibody, CpipJ_CPIJ001208 antibody, CpipJ_CPIJ001209 antibody, AIRE antibody, Aire antibody
- 背景
-
Background: Transcriptional regulator that binds to DNA as a dimer or as a tetramer, but not as a monomer. Binds to G-doublets in an A/T-rich environment, the preferred motif is a tandem repeat of 5\'-. ATTGGTTA-3\' combined with a 5\'-TTATTA-3\' box. Binds to nucleosomes (By similarity). Binds to chromatin and interacts selectively with histone H3 that is not methylated at \'Lys-4\', not phosphorylated at \'Thr-3\' and not methylated at \'Arg-2\'. Functions as a sensor of histone H3 modifications that are important for the epigenetic regulation of gene expression. Functions as a transcriptional activator and promotes the expression of otherwise tissue-specific self-antigens in the thymus, which is important for self tolerance and the avoidance of autoimmune reactions.
Aliases: AIRE antibody, AIRE_HUMAN antibody, AIRE1 antibody, APECED antibody, APECED protein antibody, APS1 antibody, APSI antibody, Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein antibody, Autoimmune regulator antibody, Autoimmune regulator protein antibody, PGA1 antibody
- UniProt
- O43918
- 途径
- Chromatin Binding
-
You are here:
