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Aurora A 抗体 (AA 1-131)

AURKA 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7145075
发货至: 中国
  • 抗原 See all Aurora A (AURKA) 抗体
    Aurora A (AURKA) (Aurora Kinase A (AURKA))
    抗原表位
    • 22
    • 16
    • 9
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    AA 1-131
    适用
    • 109
    • 70
    • 37
    • 21
    • 18
    • 12
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    宿主
    • 110
    • 16
    • 1
    克隆类型
    • 104
    • 22
    多克隆
    标记
    • 73
    • 9
    • 6
    • 6
    • 3
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    • 1
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    This Aurora A antibody is un-conjugated
    应用范围
    • 93
    • 51
    • 31
    • 21
    • 15
    • 11
    • 10
    • 7
    • 6
    • 3
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
    交叉反应
    人, 小鼠
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human Aurora kinase A protein (1-131AA)
    亚型
    IgG
    Top Product
    Discover our top product AURKA Primary Antibody
  • 应用备注
    Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200, IF:1:50-1:200,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    Aurora A (AURKA) (Aurora Kinase A (AURKA))
    别名
    AURKA (AURKA 产品)
    别名
    AIK antibody, ARK1 antibody, AURA antibody, AURORA2 antibody, BTAK antibody, PPP1R47 antibody, STK15 antibody, STK6 antibody, STK7 antibody, AIRK1 antibody, AU019385 antibody, AW539821 antibody, Ark1 antibody, Aurora-A antibody, Ayk1 antibody, IAK antibody, IAK1 antibody, Stk6 antibody, 87A7-9/2 antibody, Aur-A antibody, AurA antibody, CG3068 antibody, Dmel\\CG3068 antibody, aur-A antibody, aurA antibody, ck10 antibody, ck[10] antibody, l(3)87Ac antibody, l(3)ck10 antibody, ARK-1 antibody, Eg2 antibody, aik antibody, ark1 antibody, aur-a antibody, aura antibody, aurka-a antibody, aurora2 antibody, btak antibody, stk15 antibody, stk6 antibody, stk7 antibody, pEg2 antibody, wu:fb37c10 antibody, wu:fc02c02 antibody, zgc:100912 antibody, AURKA antibody, aurka antibody, aurora kinase A antibody, aurora A antibody, aurora kinase A L homeolog antibody, hypothetical protein antibody, aurora kinase A S homeolog antibody, AURKA antibody, Aurka antibody, aurA antibody, aurka.L antibody, aurka antibody, Aurora-A antibody, aurka.S antibody
    背景

    Background: Mitotic serine/threonine kinases that contributes to the regulation of cell cycle progression. Associates with the centrosome and the spindle microtubules during mitosis and plays a critical role in various mitotic events including the establishment of mitotic spindle, centrosome duplication, centrosome separation as well as maturation, chromosomal alignment, spindle assembly checkpoint, and cytokinesis. Required for initial activation of CDK1 at centrosomes. Phosphorylates numerous target proteins, including ARHGEF2, BORA, BRCA1, CDC25B, DLGP5, HDAC6, KIF2A, LATS2, NDEL1, PARD3, PPP1R2, PLK1, RASSF1, TACC3, p53/TP53 and TPX2. Regulates KIF2A tubulin depolymerase activity. Required for normal axon formation. Plays a role in microtubule remodeling during neurite extension. Important for microtubule formation and/or stabilization. Also acts as a key regulatory component of the p53/TP53 pathway, and particularly the checkpoint-response pathways critical for oncogenic transformation of cells, by phosphorylating and stabilizing p53/TP53. Phosphorylates its own inhibitors, the protein phosphatase type 1 (PP1) isoforms, to inhibit their activity. Necessary for proper cilia disassembly prior to mitosis.

    Aliases: AIK antibody, ARK-1 antibody, ARK1 antibody, AURA antibody, Aurka antibody, Aurora 2 antibody, Aurora A antibody, Aurora kinase A antibody, Aurora-related kinase 1 antibody, Aurora/IPL1 like kinase antibody, AURORA/IPL1-like kinase antibody, Aurora/IPL1-related kinase 1 antibody, AURORA2 antibody, Breast tumor-amplified kinase antibody, BTAK antibody, hARK1 antibody, IAK antibody, IPL1 related kinase antibody, MGC34538 antibody, OTTHUMP00000031340 antibody, OTTHUMP00000031341 antibody, OTTHUMP00000031342 antibody, OTTHUMP00000031343 antibody, OTTHUMP00000031344 antibody, OTTHUMP00000031345 antibody, OTTHUMP00000166071 antibody, OTTHUMP00000166072 antibody, PPP1R47 antibody, Protein phosphatase 1, regulatory subunit 47 antibody, Serine/threonine kinase 15 antibody, Serine/threonine kinase 6 antibody, Serine/threonine protein kinase 15 antibody, Serine/threonine-protein kinase 15 antibody, Serine/threonine-protein kinase 6 antibody, Serine/threonine-protein kinase aurora-A antibody, STK15 antibody, STK6 antibody, STK6_HUMAN antibody, STK7 antibody

    UniProt
    O14965
    途径
    Cell Division Cycle, Asymmetric Protein Localization
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