PIF1 抗体 (AA 125-360) (Biotin)
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- 抗原 See all PIF1 抗体
- PIF1 (PIF1 5'-To-3' DNA Helicase (PIF1))
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抗原表位
- AA 125-360
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PIF1 antibody is conjugated to Biotin
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应用范围
- ELISA
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human ATP-dependent DNA helicase PIF1 protein (125-360AA)
- 亚型
- IgG
- Top Product
- Discover our top product PIF1 Primary Antibody
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- PIF1 (PIF1 5'-To-3' DNA Helicase (PIF1))
- 别名
- PIF1 (PIF1 产品)
- 别名
- C15orf20 antibody, PIF antibody, 4631410M14 antibody, AI449441 antibody, cb934 antibody, fe11d03 antibody, wu:fe11d03 antibody, zgc:56161 antibody, PIF1 5'-to-3' DNA helicase antibody, PIF1 5'-to-3' DNA helicase homolog (S. cerevisiae) antibody, PIF1 antibody, Pif1 antibody, pif1.L antibody, pif1 antibody
- 背景
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Background: DNA-dependent ATPase and 5\\\'-3\\\' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. Efficiently unwinds G-quadruplex (G4) DNA structures and forked RNA-DNA hybrids. Resolves G4 structures, preventing replication pausing and double-strand breaks (DSBs) at G4 motifs. Involved in the maintenance of telomeric DNA. Inhibits telomere elongation, de novo telomere formation and telomere addition to DSBs via catalytic inhibition of telomerase. Reduces the processivity of telomerase by displacing active telomerase from DNA ends. Releases telomerase by unwinding the short telomerase RNA/telomeric DNA hybrid that is the intermediate in the telomerase reaction. Possesses an intrinsic strand annealing activity.
Aliases: ATP dependent DNA helicase PIF1 antibody, ATP-dependent DNA helicase PIF1 antibody, C15orf20 antibody, DNA helicase homolog PIF1 antibody, DNA helicase PIF1 antibody, DNA repair and recombination helicase PIF1 antibody, Petite integration frequency 1 antibody, PIF antibody, PIF1 5' to 3' DNA helicase antibody, PIF1 5' to 3' DNA helicase homolog antibody, PIF1 antibody, PIF1 DNA helicase antibody, PIF1/RRM3 DNA helicase like protein antibody, PIF1/RRM3 DNA helicase-like protein antibody, PIF1_HUMAN antibody
- UniProt
- Q9H611
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