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Ataxin 3 抗体 (AA 1-288)

ATXN3 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7144793
发货至: 中国
  • 抗原 See all Ataxin 3 (ATXN3) 抗体
    Ataxin 3 (ATXN3)
    抗原表位
    • 15
    • 8
    • 7
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-288
    适用
    • 55
    • 31
    • 30
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    宿主
    • 52
    • 2
    • 1
    克隆类型
    • 54
    • 1
    多克隆
    标记
    • 23
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Ataxin 3 antibody is un-conjugated
    应用范围
    • 43
    • 18
    • 16
    • 13
    • 13
    • 12
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    交叉反应
    人, 小鼠
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human Ataxin-3 protein (1-288AA)
    亚型
    IgG
    Top Product
    Discover our top product ATXN3 Primary Antibody
  • 应用备注
    Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    Ataxin 3 (ATXN3)
    别名
    ATXN3 (ATXN3 产品)
    别名
    Mjd antibody, zgc:56323 antibody, ATXN3 antibody, at3 antibody, jos antibody, mjd antibody, atx3 antibody, mjd1 antibody, sca3 antibody, ataxin-3 antibody, MJD1 antibody, MGC83584 antibody, AT3 antibody, ATX3 antibody, JOS antibody, MJD antibody, SCA3 antibody, 2210008M02Rik antibody, AI463012 antibody, AI647473 antibody, Sca3 antibody, Rsca3 antibody, ataxin 3 antibody, ataxin 3 L homeolog antibody, ataxin-3 antibody, atxn3 antibody, ATXN3 antibody, atxn3.L antibody, MICPUN_104046 antibody, MICPUCDRAFT_46658 antibody, Atxn3 antibody
    背景

    Background: Deubiquitinating enzyme involved in protein homeostasis maintenance, transcription, cytoskeleton regulation, myogenesis and degradation of misfolded chaperone substrates. Binds long polyubiquitin chains and trims them, while it has weak or no activity against chains of 4 or less ubiquitins. Involved in degradation of misfolded chaperone substrates via its interaction with STUB1/CHIP: recruited to monoubiquitinated STUB1/CHIP, and restricts the length of ubiquitin chain attached to STUB1/CHIP substrates and preventing further chain extension. In response to misfolded substrate ubiquitination, mediates deubiquitination of monoubiquitinated STUB1/CHIP. Interacts with key regulators of transcription and represses transcription: acts as a histone-binding protein that regulates transcription.

    Aliases: AT3 antibody, Ataxin 3 antibody, ataxin 3 variant h antibody, ataxin 3 variant m antibody, ataxin 3 variant ref antibody, Ataxin-3 antibody, ATX3 antibody, ATX3_HUMAN antibody, ATXN3 antibody, EC 3.4.22. antibody, JOS antibody, Josephin antibody, Machado Joseph disease (spinocerebellar ataxia 3, olivopontocerebellar ataxia 3, autosomal dominant, ataxin 3) antibody, Machado Joseph disease antibody, Machado Joseph disease protein 1 antibody, Machado-Joseph disease protein 1 antibody, Machado-Joseph disease protein 1 homolog antibody, MJD antibody, MJD gene antibody, MJD1 antibody, Olivopontocerebellar ataxia 3 antibody, OTTHUMP00000221583 antibody, OTTHUMP00000221585 antibody, OTTHUMP00000221586 antibody, OTTHUMP00000221587 antibody, OTTHUMP00000231995 antibody, OTTHUMP00000231997 antibody, Rsca3 antibody, SCA3 antibody, SCA3 gene antibody, Spinocerebellar ataxia type 3 protein antibody

    UniProt
    P54252
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