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Asporin 抗体 (AA 33-380)

ASPN 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7144761
发货至: 中国
  • 抗原 See all Asporin (ASPN) 抗体
    Asporin (ASPN)
    抗原表位
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 33-380
    适用
    • 31
    • 8
    • 7
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 28
    • 3
    • 1
    克隆类型
    • 31
    • 1
    多克隆
    标记
    • 22
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Asporin antibody is un-conjugated
    应用范围
    • 21
    • 11
    • 8
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA
    交叉反应
    人, 小鼠
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human Asporin protein (33-380AA)
    亚型
    IgG
    Top Product
    Discover our top product ASPN Primary Antibody
  • 应用备注
    Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    Asporin (ASPN)
    别名
    ASPN (ASPN 产品)
    别名
    OS3 antibody, PLAP-1 antibody, PLAP1 antibody, SLRR1C antibody, bgl3 antibody, aspnl antibody, wu:fk08c11 antibody, zgc:109936 antibody, 4631401G09Rik antibody, AA986886 antibody, Plap1 antibody, Slrr1c antibody, os3 antibody, plap-1 antibody, plap1 antibody, slrr1c antibody, asporin antibody, asporin (LRR class 1) antibody, asporin L homeolog antibody, ASPN antibody, aspn antibody, Aspn antibody, aspn.L antibody
    背景

    Background: Negatively regulates periodontal ligament (PDL) differentiation and mineralization to ensure that the PDL is not ossified and to maintain homeostasis of the tooth-supporting system. Inhibits BMP2-induced cytodifferentiation of PDL cells by preventing its binding to BMPR1B/BMP type-1B receptor, resulting in inhibition of BMP-dependent activation of SMAD proteins (By similarity). Critical regulator of TGF-beta in articular cartilage and plays an essential role in cartilage homeostasis and osteoarthritis (OA) pathogenesis. Negatively regulates chondrogenesis in the articular cartilage by blocking the TGF-beta/receptor interaction on the cell surface and inhibiting the canonical TGF-beta/Smad signal. Binds calcium and plays a role in osteoblast-driven collagen biomineralization activity.

    Aliases: ASPN antibody, ASPN protein antibody, ASPN_HUMAN antibody, Asporin (LRR class 1) antibody, Asporin antibody, Asporin proteoglycan antibody, FLJ20129 antibody, LRR class 1 antibody, Periodontal ligament associated protein 1 antibody, Periodontal ligament-associated protein 1 antibody, PLAP 1 antibody, PLAP-1 antibody, PLAP1 antibody, SLRR 1C antibody, SLRR1C antibody, Small leucine rich protein 1C antibody

    UniProt
    Q9BXN1
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