ALOX12B 抗体 (AA 484-663) (FITC)
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- 抗原 See all ALOX12B 抗体
- ALOX12B (Arachidonate 12-Lipoxygenase, 12R Type (ALOX12B))
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抗原表位
- AA 484-663
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ALOX12B antibody is conjugated to FITC
- 应用范围
- 请咨询
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human Arachidonate 12-lipoxygenase, 12R-type protein (484-663AA)
- 亚型
- IgG
- Top Product
- Discover our top product ALOX12B Primary Antibody
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- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- ALOX12B (Arachidonate 12-Lipoxygenase, 12R Type (ALOX12B))
- 别名
- ALOX12B (ALOX12B 产品)
- 别名
- ALOX12B antibody, MGC107915 antibody, MGC85124 antibody, 12R-LOX antibody, ARCI2 antibody, Aloxe2 antibody, e-LOX2 antibody, arachidonate 12-lipoxygenase, 12R type antibody, arachidonate 12-lipoxygenase, 12R type S homeolog antibody, ALOX12B antibody, alox12b antibody, alox12b.S antibody, Alox12b antibody
- 背景
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Background: Non-heme iron-containing dioxygenase that catalyzes the stereo-specific peroxidation of free and esterified polyunsaturated fatty acids generating a spectrum of bioactive lipid mediators. Mainly converts arachidonic acid to (12R)-hydroperoxyeicosatetraenoic acid/(12R)-HPETE and minor stereoisomers. In the skin, acts upstream of ALOXE3 on the lineolate moiety of esterified omega-hydroxyacyl-sphingosine (EOS) ceramides to produce an epoxy-ketone derivative, a crucial step in the conjugation of omega-hydroxyceramide to membrane proteins. Therefore plays a crucial role in the synthesis of corneocytes lipid envelope and the establishment of the skin barrier to water loss. May also play a role in the regulation of the expression of airway mucins.
Aliases: ALOX12B antibody, Arachidonate 12-lipoxygenase antibody, 12R-type antibody, 12R-LOX antibody, 12R-lipoxygenase antibody, EC 1.13.11.- antibody, Epidermis-type lipoxygenase 12 antibody
- UniProt
- O75342
- 途径
- Cell-Cell Junction Organization
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