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- 抗原 See all AAK1 抗体
- AAK1 (AP2 associated kinase 1 (AAK1))
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抗原表位
- AA 274-465
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This AAK1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
- 交叉反应
- 人, 小鼠
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human AP2-associated protein kinase 1 protein (274-465AA)
- 亚型
- IgG
- Top Product
- Discover our top product AAK1 Primary Antibody
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anti-AP2 associated kinase 1 (AAK1) (AA 315-415) antibody
AAK1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4B10 unconjugated
anti-AP2 associated kinase 1 (AAK1) (AA 274-465) antibodyAAK1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-AP2 associated kinase 1 (AAK1) (C-Term) antibodyAAK1 适用: 人, 小鼠, 大鼠 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-AP2 associated kinase 1 (AAK1) (N-Term) antibodyAAK1 适用: 人, 小鼠, 大鼠 WB, IHC, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-AP2 associated kinase 1 (AAK1) (AA 301-400) antibodyAAK1 适用: 小鼠 ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-AP2 associated kinase 1 (AAK1) (N-Term) antibodyAAK1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-AP2 associated kinase 1 (AAK1) antibodyAAK1 适用: 人, 小鼠, 大鼠, Cow WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-AP2 associated kinase 1 (AAK1) (Internal Region) antibodyAAK1 适用: 人, 小鼠, 大鼠, 猴 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-AP2 associated kinase 1 (AAK1) (Internal Region) antibodyVerified AAK1 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-AP2 associated kinase 1 (AAK1) (AA 593-642) antibodyAAK1 适用: 人, 小鼠, 大鼠, 马, 猴, 兔, 犬, 小鸡 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- AAK1 (AP2 associated kinase 1 (AAK1))
- 别名
- AAK1 (AAK1 产品)
- 别名
- 5530400K14Rik antibody, 9630042K20 antibody, AU067724 antibody, AU067726 antibody, BC028270 antibody, C79663 antibody, D6Ertd245e antibody, R75501 antibody, mKIAA1048 antibody, RGD1563580 antibody, aak1 antibody, si:dkey-261l11.5 antibody, AP2 associated kinase 1 antibody, uncharacterized protein FLJ45252 antibody, AP2 associated kinase 1b antibody, AAK1 antibody, Aak1 antibody, LOC100512341 antibody, aak1b antibody
- 背景
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Background: Regulates clathrin-mediated endocytosis by phosphorylating the AP2M1/mu2 subunit of the adaptor protein complex 2 (AP-2) which ensures high affinity binding of AP-2 to cargo membrane proteins during the initial stages of endocytosis. Isoform 1 and isoform 2 display similar levels of kinase activity towards AP2M1. Regulates phosphorylation of other AP-2 subunits as well as AP-2 localization and AP-2-mediated internalization of ligand complexes. Phosphorylates NUMB and regulates its cellular localization, promoting NUMB localization to endosomes. Binds to and stabilizes the activated form of NOTCH1, increases its localization in endosomes and regulates its transcriptional activity.
Aliases: AAK 1 antibody, Aak1 antibody, AAK1_HUMAN antibody, Adaptor associated kinase 1 antibody, Adaptor-associated kinase 1 antibody, AP2 associated kinase 1 antibody, AP2 associated protein kinase 1 antibody, AP2-associated protein kinase 1 antibody, DKFZp686F03202 antibody, DKFZp686K16132 antibody, FLJ23712 antibody, FLJ25931 antibody, FLJ31060 antibody, FLJ42882 antibody, FLJ45252 antibody, KIAA1048 antibody, MGC138170 antibody, MGC164568 antibody, MGC164570 antibody
- UniProt
- Q2M2I8
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