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ALKBH8 抗体 (AA 1-230)

ALKBH8 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7143718
发货至: 中国
  • 抗原 See all ALKBH8 抗体
    ALKBH8 (AlkB, Alkylation Repair Homolog 8 (ALKBH8))
    抗原表位
    • 15
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 1-230
    适用
    • 19
    • 16
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    宿主
    • 34
    克隆类型
    • 34
    多克隆
    标记
    • 13
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ALKBH8 antibody is un-conjugated
    应用范围
    • 13
    • 13
    • 11
    • 7
    • 5
    • 5
    • 3
    • 2
    • 1
    • 1
    ELISA, Immunohistochemistry (IHC)
    交叉反应
    纯化方法
    Antigen Affinity Purified
    免疫原
    Recombinant Human Alkylated DNA repair protein alkB homolog 8 protein (1-230AA)
    亚型
    IgG
    Top Product
    Discover our top product ALKBH8 Primary Antibody
  • 应用备注
    Recommended dilution: IHC:1:20-1:200,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    ALKBH8 (AlkB, Alkylation Repair Homolog 8 (ALKBH8))
    别名
    ALKBH8 (ALKBH8 产品)
    别名
    ABH8 antibody, 4930562C03Rik antibody, 8030431D03Rik antibody, 9430088N01Rik antibody, Abh8 antibody, alkB homolog 8, tRNA methyltransferase antibody, ALKBH8 antibody, Alkbh8 antibody
    背景

    Background: Catalyzes the methylation of 5-carboxymethyl uridine to 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in tRNA via its methyltransferase domain (PubMed:20123966, PubMed:20308323). Catalyzes the last step in the formation of 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in target tRNA (PubMed:20123966, PubMed:20308323). Has a preference for tRNA(Arg) and tRNA(Glu), and does not bind tRNA(Lys)(PubMed:20308323). Binds tRNA and catalyzes the iron and alpha-ketoglutarate dependent hydroxylation of 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in tRNA via its dioxygenase domain, giving rise to 5-(S)-methoxycarbonylhydroxymethyluridine, has a preference for tRNA(Gly) (PubMed:21285950). Required for normal survival after DNA damage (PubMed:20308323). May inhibit apoptosis and promote cell survival and angiogenesis (PubMed:19293182).

    Aliases: 4930562C03Rik antibody, 8030431D03Rik antibody, 9430088N01Rik antibody, ABH8 antibody, alkB alkylation repair homolog 8 (E. coli) antibody, alkB alkylation repair homolog 8 antibody, AlkB homologue 8 antibody, ALKB8_HUMAN antibody, ALKBH8 antibody, Alkylated DNA repair protein alkB homolog 8 antibody, FLJ38204 antibody, MGC10235 antibody, OTTHUMP00000211286 antibody, OTTHUMP00000211287 antibody, Probable alpha-ketoglutarate-dependent dioxygenase ABH8 antibody, RGD1304687 antibody, S-adenosyl-L-methionine-dependent tRNA methyltransferase ABH8 antibody, tRNA (carboxymethyluridine(34)-5-O)-methyltransferase ABH8 antibody

    UniProt
    Q96BT7
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