ALKBH8 抗体 (AA 1-230)
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- 抗原 See all ALKBH8 抗体
- ALKBH8 (AlkB, Alkylation Repair Homolog 8 (ALKBH8))
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抗原表位
- AA 1-230
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ALKBH8 antibody is un-conjugated
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应用范围
- ELISA, Immunohistochemistry (IHC)
- 交叉反应
- 人
- 纯化方法
- Antigen Affinity Purified
- 免疫原
- Recombinant Human Alkylated DNA repair protein alkB homolog 8 protein (1-230AA)
- 亚型
- IgG
- Top Product
- Discover our top product ALKBH8 Primary Antibody
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- 应用备注
- Recommended dilution: IHC:1:20-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- ALKBH8 (AlkB, Alkylation Repair Homolog 8 (ALKBH8))
- 别名
- ALKBH8 (ALKBH8 产品)
- 别名
- ABH8 antibody, 4930562C03Rik antibody, 8030431D03Rik antibody, 9430088N01Rik antibody, Abh8 antibody, alkB homolog 8, tRNA methyltransferase antibody, ALKBH8 antibody, Alkbh8 antibody
- 背景
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Background: Catalyzes the methylation of 5-carboxymethyl uridine to 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in tRNA via its methyltransferase domain (PubMed:20123966, PubMed:20308323). Catalyzes the last step in the formation of 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in target tRNA (PubMed:20123966, PubMed:20308323). Has a preference for tRNA(Arg) and tRNA(Glu), and does not bind tRNA(Lys)(PubMed:20308323). Binds tRNA and catalyzes the iron and alpha-ketoglutarate dependent hydroxylation of 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in tRNA via its dioxygenase domain, giving rise to 5-(S)-methoxycarbonylhydroxymethyluridine, has a preference for tRNA(Gly) (PubMed:21285950). Required for normal survival after DNA damage (PubMed:20308323). May inhibit apoptosis and promote cell survival and angiogenesis (PubMed:19293182).
Aliases: 4930562C03Rik antibody, 8030431D03Rik antibody, 9430088N01Rik antibody, ABH8 antibody, alkB alkylation repair homolog 8 (E. coli) antibody, alkB alkylation repair homolog 8 antibody, AlkB homologue 8 antibody, ALKB8_HUMAN antibody, ALKBH8 antibody, Alkylated DNA repair protein alkB homolog 8 antibody, FLJ38204 antibody, MGC10235 antibody, OTTHUMP00000211286 antibody, OTTHUMP00000211287 antibody, Probable alpha-ketoglutarate-dependent dioxygenase ABH8 antibody, RGD1304687 antibody, S-adenosyl-L-methionine-dependent tRNA methyltransferase ABH8 antibody, tRNA (carboxymethyluridine(34)-5-O)-methyltransferase ABH8 antibody
- UniProt
- Q96BT7
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