ACD 抗体 (AA 328-497) (HRP)
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- 抗原 See all ACD 抗体
- ACD (Adrenocortical Dysplasia Homolog (ACD))
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抗原表位
- AA 328-497
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ACD antibody is conjugated to HRP
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应用范围
- ELISA
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human Adrenocortical dysplasia protein homolog protein (328-497AA)
- 亚型
- IgG
- Top Product
- Discover our top product ACD Primary Antibody
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- ACD (Adrenocortical Dysplasia Homolog (ACD))
- 别名
- ACD (ACD 产品)
- 别名
- PIP1 antibody, PTOP antibody, TINT1 antibody, TPP1 antibody, ACD antibody, ACD, shelterin complex subunit and telomerase recruitment factor antibody, adrenocortical dysplasia antibody, ACD antibody, Acd antibody
- 背景
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Background: Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded TTAGGG repeats added by telomerase and protects chromosome ends. Without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways. Promotes binding of POT1 to single-stranded telomeric DNA. Modulates the inhibitory effects of POT1 on telomere elongation. The ACD-POT1 heterodimer enhances telomere elongation by recruiting telomerase to telomeres and increasing its processivity. May play a role in organogenesis.
Aliases: Acd antibody, ACD_HUMAN antibody, Adrenocortical dysplasia homolog antibody, Adrenocortical dysplasia protein homolog antibody, PIP1 antibody, POT1 and TIN2 organizing protein antibody, POT1 and TIN2-interacting protein antibody, TIN2 interacting protein 1 antibody, TINT1 antibody, TPP1 antibody
- UniProt
- Q96AP0
- 途径
- Telomere Maintenance
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