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ACD 抗体 (AA 328-497)

ACD 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7143546
发货至: 中国
  • 抗原 See all ACD 抗体
    ACD (Adrenocortical Dysplasia Homolog (ACD))
    抗原表位
    • 5
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 328-497
    适用
    • 31
    • 12
    • 7
    • 3
    • 3
    • 3
    • 3
    • 1
    宿主
    • 26
    • 7
    • 1
    克隆类型
    • 29
    • 5
    多克隆
    标记
    • 23
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ACD antibody is un-conjugated
    应用范围
    • 23
    • 9
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    交叉反应
    人, 小鼠
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human Adrenocortical dysplasia protein homolog protein (328-497AA)
    亚型
    IgG
    Top Product
    Discover our top product ACD Primary Antibody
  • 应用备注
    Recommended dilution: WB:1:500-1:5000,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    ACD (Adrenocortical Dysplasia Homolog (ACD))
    别名
    ACD (ACD 产品)
    别名
    PIP1 antibody, PTOP antibody, TINT1 antibody, TPP1 antibody, ACD antibody, ACD, shelterin complex subunit and telomerase recruitment factor antibody, adrenocortical dysplasia antibody, ACD antibody, Acd antibody
    背景

    Background: Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded TTAGGG repeats added by telomerase and protects chromosome ends. Without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways. Promotes binding of POT1 to single-stranded telomeric DNA. Modulates the inhibitory effects of POT1 on telomere elongation. The ACD-POT1 heterodimer enhances telomere elongation by recruiting telomerase to telomeres and increasing its processivity. May play a role in organogenesis.

    Aliases: Acd antibody, ACD_HUMAN antibody, Adrenocortical dysplasia homolog antibody, Adrenocortical dysplasia protein homolog antibody, PIP1 antibody, POT1 and TIN2 organizing protein antibody, POT1 and TIN2-interacting protein antibody, TIN2 interacting protein 1 antibody, TINT1 antibody, TPP1 antibody

    UniProt
    Q96AP0
    途径
    Telomere Maintenance
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