MOCS3 抗体 (AA 279-404)
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- 抗原 See all MOCS3 抗体
- MOCS3 (Molybdenum Cofactor Synthesis 3 (MOCS3))
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抗原表位
- AA 279-404
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MOCS3 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 交叉反应
- 人, 小鼠
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human Adenylyltransferase and sulfurtransferase MOCS3 protein (279-404aa)
- 亚型
- IgG
- Top Product
- Discover our top product MOCS3 Primary Antibody
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- 应用备注
- Recommended dilution: WB:1:1000-1:5000,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- MOCS3 (Molybdenum Cofactor Synthesis 3 (MOCS3))
- 别名
- MOCS3 (MOCS3 产品)
- 别名
- MOCS3 antibody, DDBDRAFT_0189692 antibody, DDBDRAFT_0267172 antibody, DDB_0189692 antibody, DDB_0267172 antibody, UBA4 antibody, 1700020H17Rik antibody, Uba4 antibody, zgc:55696 antibody, uba4 antibody, molybdenum cofactor synthesis 3 antibody, molybdenum cofactor synthesis 3 L homeolog antibody, MOCS3 antibody, mocs3 antibody, Mocs3 antibody, mocs3.L antibody
- 背景
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Background: Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers URM1 and MOCS2A. Its N-terminus first activates URM1 and MOCS2A as acyl-adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 and MOCS2A to form thiocarboxylation (-COSH) of their C-terminus. The reaction probably involves hydrogen sulfide that is generated from the persulfide intermediate and that acts as nucleophile towards URM1 and MOCS2A. Subsequently, a transient disulfide bond is formed. Does not use thiosulfate as sulfur donor, NFS1 probably acting as a sulfur donor for thiocarboxylation reactions.
Aliases: Adenylyltransferase and sulfurtransferase MOCS3 (Molybdenum cofactor synthesis protein 3) (Molybdopterin synthase sulfurylase) (MPT synthase sulfurylase) [Includes: Molybdopterin-synthase adenylyltransferase (EC 2.7.7.80) (Adenylyltransferase MOCS3) (Sulfur carrier protein MOCS2A adenylyltransferase), Molybdopterin-synthase sulfurtransferase (EC 2.8.1.11) (Sulfur carrier protein MOCS2A sulfurtransferase) (Sulfurtransferase MOCS3)], MOCS3, UBA4
- UniProt
- O95396
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