ADCY6 抗体 (AA 9-118)
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- 抗原 See all ADCY6 抗体
- ADCY6 (Adenylate Cyclase 6 (ADCY6))
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抗原表位
- AA 9-118
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ADCY6 antibody is un-conjugated
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应用范围
- ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human Adenylate cyclase type 6 protein (9-118AA)
- 亚型
- IgG
- Top Product
- Discover our top product ADCY6 Primary Antibody
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- 应用备注
- Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- ADCY6 (Adenylate Cyclase 6 (ADCY6))
- 别名
- ADCY6 (ADCY6 产品)
- 别名
- ADCY6 antibody, adcy6 antibody, AC6 antibody, mKIAA0422 antibody, ACVI antibody, ADCYB antibody, adenylate cyclase 6 L homeolog antibody, adenylate cyclase 6 antibody, adenylate cyclase 6a antibody, adcy6.L antibody, ADCY6 antibody, adcy6a antibody, adcy6 antibody, Adcy6 antibody
- 背景
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Background: Catalyzes the formation of the signaling molecule cAMP downstream of G protein-coupled receptors (PubMed:17916776, PubMed:17110384). Functions in signaling cascades downstream of beta-adrenergic receptors in the heart and in vascular smooth muscle cells (PubMed:17916776). Functions in signaling cascades downstream of the vasopressin receptor in the kidney and has a role in renal water reabsorption. Functions in signaling cascades downstream of PTH1R and plays a role in regulating renal phosphate excretion. Functions in signaling cascades downstream of the VIP and SCT receptors in pancreas and contributes to the regulation of pancreatic amylase and fluid secretion (By similarity). Signaling mediates cAMP-dependent activation of protein kinase PKA. This promotes increased phosphorylation of various proteins, including AKT. Plays a role in regulating cardiac sarcoplasmic reticulum Ca(2+) uptake and storage, and is required for normal heart ventricular contractibility. May contribute to normal heart function (By similarity). Mediates vasodilatation after activation of beta-adrenergic receptors by isoproterenol (PubMed:17916776). Contributes to bone cell responses to mechanical stimuli (By similarity).
Aliases: AC6 antibody, ACVI antibody, ADCY 6 antibody, Adcy6 antibody, ADCY6_HUMAN antibody, ADCYB antibody, Adenylate cyclase 6 antibody, Adenylate cyclase type 6 antibody, Adenylate cyclase type VI antibody, Adenylyl cyclase 6 antibody, ATP pyrophosphate lyase 6 antibody, ATP pyrophosphate-lyase 6 antibody, Ca(2+) inhibitable adenylyl cyclase antibody, Ca(2+)-inhibitable adenylyl cyclase antibody, DKFZp779F075 antibody, EC 4.6.1.1 antibody, KIAA0422 antibody
- UniProt
- O43306
- 途径
- EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, cAMP Metabolic Process, Myometrial Relaxation and Contraction, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma
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