ARPC2 抗体 (AA 1-250) (HRP)
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- 抗原 See all ARPC2 抗体
- ARPC2 (Actin Related Protein 2/3 Complex, Subunit 2, 34kDa (ARPC2))
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抗原表位
- AA 1-250
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ARPC2 antibody is conjugated to HRP
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应用范围
- ELISA
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human Actin-related protein 2/3 complex subunit 2 protein (1-250AA)
- 亚型
- IgG
- Top Product
- Discover our top product ARPC2 Primary Antibody
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- ARPC2 (Actin Related Protein 2/3 Complex, Subunit 2, 34kDa (ARPC2))
- 别名
- ARPC2 (ARPC2 产品)
- 别名
- arc34 antibody, p34-arc antibody, pnas-139 antibody, pro2446 antibody, Arpc2 antibody, Arc-p34 antibody, 2210023N03Rik antibody, 34kDa antibody, p34-Arc antibody, fk84a07 antibody, wu:fa22f07 antibody, wu:fk84a07 antibody, zgc:77769 antibody, ARC34 antibody, PNAS-139 antibody, actin related protein 2/3 complex subunit 2 antibody, actin related protein 2/3 complex, subunit 2, 34kDa antibody, actin related protein 2/3 complex, subunit 2 antibody, actin related protein 2/3 complex subunit 2 S homeolog antibody, ARPC2 antibody, arpc2 antibody, Arpc2 antibody, arpc2.S antibody
- 背景
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Background: Actin-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF) (PubMed:9230079). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility (PubMed:9230079). Seems to contact the mother actin filament (PubMed:9230079). In addition to its role in the cytoplasmic cytoskeleton, the Arp2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA (PubMed:29925947). The Arp2/3 complex promotes homologous recombination (HR) repair in response to DNA damage by promoting nuclear actin polymerization, leading to drive motility of double-strand breaks (DSBs) (PubMed:29925947).
Aliases: Actin related protein 2/3 complex subunit 2 34 kDa antibody, Actin related protein 2/3 complex subunit 2 antibody, Actin-related protein 2/3 complex subunit 2 antibody, ARC 34 antibody, ARC34 antibody, Arp2/3 complex 34 kDa subunit antibody, ARP2/3 protein compex subunit 34 antibody, ARPC 2 antibody, Arpc2 antibody, ARPC2_HUMAN antibody, p34 Arc antibody, p34-ARC antibody, p34Arc antibody, PNAS 139 antibody, PNAS139 antibody, PRO 2446 antibody, PRO2446 antibody
- UniProt
- O15144
- 途径
- RTK signaling, Regulation of Actin Filament Polymerization
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