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Actin-Like 6B 抗体 (AA 1-280)

ACTL6B 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7143053
发货至: 中国
  • 抗原 See all Actin-Like 6B (ACTL6B) 抗体
    Actin-Like 6B (ACTL6B)
    抗原表位
    • 8
    • 8
    • 6
    • 1
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    AA 1-280
    适用
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    • 2
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    宿主
    • 31
    • 1
    克隆类型
    • 31
    • 1
    多克隆
    标记
    • 15
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    This Actin-Like 6B antibody is un-conjugated
    应用范围
    • 25
    • 18
    • 15
    • 13
    • 5
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA
    交叉反应
    纯化方法
    Antigen Affinity Purified
    免疫原
    Recombinant Human Actin-like protein 6B protein (1-280AA)
    亚型
    IgG
    Top Product
    Discover our top product ACTL6B Primary Antibody
  • 应用备注
    Recommended dilution: WB:1:200-1:1000, IHC:1:20-1:200,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    Actin-Like 6B (ACTL6B)
    别名
    ACTL6B (ACTL6B 产品)
    别名
    MGC110167 antibody, zgc:110167 antibody, ACTL6 antibody, BAF53B antibody, Actl6 antibody, ArpNa antibody, Baf53b antibody, actin-like 6B antibody, actin like 6B antibody, actl6b antibody, ACTL6B antibody, Actl6b antibody
    背景

    Background: Belongs to the chromatin remodeling brain-specific BAF (bBAF) complex, as such plays a role in remodeling mononucleosomes in an ATP-dependent fashion. Belongs to the neuron-specific chromatin remodeling complex (nBAF complex) and is required for postmitotic neural development and dendritic outgrowth. During neural development a switch from a stem/progenitor to a post-mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to post-mitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes. As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific complexes (nBAF). The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells. The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth. ACTL6B/BAF53B is not essential for assembly of the nBAF complex but is required for targeting the complex and CREST to the promoter of genes essential for dendritic growth .

    Aliases: 53 kDa BRG1 associated factor B antibody, 53 kDa BRG1-associated factor B antibody, ACL 6B antibody, ACL6B antibody, ACL6B_HUMAN antibody, Actin like 6 antibody, Actin like protein 6B antibody, Actin like protein6B antibody, Actin related protein antibody, Actin related protein Baf53b antibody, actin-like 6B antibody, Actin-like protein 6B antibody, Actin-related protein Baf53b antibody, Actl 6 antibody, ACTL 6B antibody, Actl6 antibody, ACTL6 B antibody, Actl6b antibody, Arp Na antibody, ArpN a antibody, ArpN alpha antibody, ArpNa antibody, ArpNalpha antibody, Baf 53b antibody, BAF53B antibody, BRG1-associated factor 53B antibody

    UniProt
    O94805
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