Actin-Like 6B 抗体 (AA 1-280)
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- 抗原 See all Actin-Like 6B (ACTL6B) 抗体
- Actin-Like 6B (ACTL6B)
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抗原表位
- AA 1-280
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Actin-Like 6B antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA
- 交叉反应
- 人
- 纯化方法
- Antigen Affinity Purified
- 免疫原
- Recombinant Human Actin-like protein 6B protein (1-280AA)
- 亚型
- IgG
- Top Product
- Discover our top product ACTL6B Primary Antibody
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- 应用备注
- Recommended dilution: WB:1:200-1:1000, IHC:1:20-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- Actin-Like 6B (ACTL6B)
- 别名
- ACTL6B (ACTL6B 产品)
- 别名
- MGC110167 antibody, zgc:110167 antibody, ACTL6 antibody, BAF53B antibody, Actl6 antibody, ArpNa antibody, Baf53b antibody, actin-like 6B antibody, actin like 6B antibody, actl6b antibody, ACTL6B antibody, Actl6b antibody
- 背景
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Background: Belongs to the chromatin remodeling brain-specific BAF (bBAF) complex, as such plays a role in remodeling mononucleosomes in an ATP-dependent fashion. Belongs to the neuron-specific chromatin remodeling complex (nBAF complex) and is required for postmitotic neural development and dendritic outgrowth. During neural development a switch from a stem/progenitor to a post-mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to post-mitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes. As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific complexes (nBAF). The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells. The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth. ACTL6B/BAF53B is not essential for assembly of the nBAF complex but is required for targeting the complex and CREST to the promoter of genes essential for dendritic growth .
Aliases: 53 kDa BRG1 associated factor B antibody, 53 kDa BRG1-associated factor B antibody, ACL 6B antibody, ACL6B antibody, ACL6B_HUMAN antibody, Actin like 6 antibody, Actin like protein 6B antibody, Actin like protein6B antibody, Actin related protein antibody, Actin related protein Baf53b antibody, actin-like 6B antibody, Actin-like protein 6B antibody, Actin-related protein Baf53b antibody, Actl 6 antibody, ACTL 6B antibody, Actl6 antibody, ACTL6 B antibody, Actl6b antibody, Arp Na antibody, ArpN a antibody, ArpN alpha antibody, ArpNa antibody, ArpNalpha antibody, Baf 53b antibody, BAF53B antibody, BRG1-associated factor 53B antibody
- UniProt
- O94805
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