AKAP1 抗体 (AA 413-662)
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- 抗原 See all AKAP1 抗体
- AKAP1 (A Kinase (PRKA) Anchor Protein 1 (AKAP1))
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抗原表位
- AA 413-662
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This AKAP1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA
- 交叉反应
- 人
- 纯化方法
- Antigen Affinity Purified
- 免疫原
- Recombinant Human A-kinase anchor protein 10, mitochondrial protein (413-662AA)
- 亚型
- IgG
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- 应用备注
- Recommended dilution: WB:1:200-1:1000, IHC:1:20-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- AKAP1 (A Kinase (PRKA) Anchor Protein 1 (AKAP1))
- 别名
- AKAP1 (AKAP1 产品)
- 别名
- AKAP1 antibody, akap1 antibody, fa08b04 antibody, wu:fa08b04 antibody, AKAP antibody, AKAP121 antibody, AKAP149 antibody, AKAP84 antibody, D-AKAP1 antibody, PPP1R43 antibody, PRKA1 antibody, SAKAP84 antibody, TDRD17 antibody, Akap antibody, C76494 antibody, C81186 antibody, DAKAP1 antibody, S-AKAP84 antibody, Akap84 antibody, A-kinase anchoring protein 1 antibody, A kinase (PRKA) anchor protein 1b antibody, A kinase (PRKA) anchor protein 1 antibody, AKAP1 antibody, akap1b antibody, akap1 antibody, Akap1 antibody
- 背景
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Background: Differentially targeted protein that binds to type I and II regulatory subunits of protein kinase A and anchors them to the mitochondria or the plasma membrane. Although the physiological relevance between PKA and AKAPS with mitochondria is not fully understood, one idea is that BAD, a proapoptotic member, is phosphorylated and inactivated by mitochondria-anchored PKA. It cannot be excluded too that it may facilitate PKA as well as G protein signal transduction, by acting as an adapter for assembling multiprotein complexes. With its RGS domain, it could lead to the interaction to G-alpha proteins, providing a link between the signaling machinery and the downstream kinase (By similarity).
Aliases: AKAP10A-kinase anchor protein 10 antibody, mitochondrial antibody, AKAP-10 antibody, Dual specificity A kinase-anchoring protein 2 antibody, D-AKAP-2 antibody, Protein kinase A-anchoring protein 10 antibody, PRKA10 antibody
- UniProt
- O43572
- 途径
- Synaptic Membrane
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