RPL13A 抗体 (AA 63-190)
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- 抗原 See all RPL13A 抗体
- RPL13A (Ribosomal Protein L13a (RPL13A))
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抗原表位
- AA 63-190
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This RPL13A antibody is un-conjugated
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应用范围
- ELISA, Immunofluorescence (IF)
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human 60S ribosomal protein L13a protein (63-190AA)
- 亚型
- IgG
- Top Product
- Discover our top product RPL13A Primary Antibody
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- 应用备注
- Recommended dilution: IF:1:50-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- RPL13A (Ribosomal Protein L13a (RPL13A))
- 别名
- RPL13A (RPL13A 产品)
- 背景
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Background: Associated with ribosomes but is not required for canonical ribosome function and has extra-ribosomal functions. Component of the GAIT (gamma interferon-activated inhibitor of translation) complex which mediates interferon-gamma-induced transcript-selective translation inhibition in inflammation processes. Upon interferon-gamma activation and subsequent phosphorylation dissociates from the ribosome and assembles into the GAIT complex which binds to stem loop-containing GAIT elements in the 3\'-UTR of diverse inflammatory mRNAs (such as ceruplasmin) and suppresses their translation. In the GAIT complex interacts with m7G cap-bound eIF4G at or near the eIF3-binding site and blocks the recruitment of the 43S ribosomal complex. Involved in methylation of rRNA.
Aliases: RPL13A antibody, 60S ribosomal protein L13a antibody, 23 kDa highly basic protein antibody, Large ribosomal subunit protein uL13 antibody
- UniProt
- P40429
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