PRKAB2 抗体 (AA 1-272)
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- 抗原 See all PRKAB2 抗体
- PRKAB2 (Protein Kinase, AMP-Activated, beta 2 Non-Catalytic Subunit (PRKAB2))
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抗原表位
- AA 1-272
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PRKAB2 antibody is un-conjugated
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应用范围
- Immunohistochemistry (IHC), ELISA
- 交叉反应
- 人
- 纯化方法
- Antigen Affinity Purified
- 免疫原
- Recombinant Human 5\\\'-AMP-activated protein kinase subunit beta-2 protein (1-272AA)
- 亚型
- IgG
- Top Product
- Discover our top product PRKAB2 Primary Antibody
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- 应用备注
- Recommended dilution: IHC:1:20-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- PRKAB2 (Protein Kinase, AMP-Activated, beta 2 Non-Catalytic Subunit (PRKAB2))
- 别名
- PRKAB2 (PRKAB2 产品)
- 别名
- prkab2 antibody, MGC64365 antibody, PRKAB2 antibody, DKFZp469M1118 antibody, 5730553K21Rik antibody, AW049591 antibody, BB124140 antibody, protein kinase, AMP-activated, beta 2 non-catalytic subunit L homeolog antibody, protein kinase AMP-activated non-catalytic subunit beta 2 antibody, protein kinase, AMP-activated, beta 2 non-catalytic subunit antibody, prkab2.L antibody, PRKAB2 antibody, prkab2 antibody, Prkab2 antibody
- 背景
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Background: Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton, probably by indirectly activating myosin. Beta non-catalytic subunit acts as a scaffold on which the AMPK complex assembles, via its C-terminus that bridges alpha (PRKAA1 or PRKAA2) and gamma subunits (PRKAG1, PRKAG2 or PRKAG3).
Aliases: 5' AMP activated protein kinase beta 2 subunit antibody, 5' AMP activated protein kinase subunit beta 2 antibody, 5''-AMP-activated protein kinase subunit beta-2 antibody, AAKB2_HUMAN antibody, AMP activated protein kinase beta 2 non catalytic subunit antibody, AMPK beta 2 antibody, AMPK beta 2 chain antibody, AMPK subunit beta 2 antibody, AMPK subunit beta-2 antibody, MGC61468 antibody, PRKAB 2 antibody, Prkab2 antibody, Protein kinase AMP activated beta 2 non catalytic subunit antibody
- UniProt
- O43741
- 途径
- AMPK Signaling, Warburg Effect
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