BRK1 抗体 (AA 31-75) (Biotin)
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- 抗原 See all BRK1 抗体
- BRK1 (BRICK1, SCAR/WAVE Actin-Nucleating Complex Subunit (BRK1))
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抗原表位
- AA 31-75
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This BRK1 antibody is conjugated to Biotin
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应用范围
- ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 预测反应
- Human,Mouse,Rat,Cow,Pig
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human hHBrk1
- 亚型
- IgG
- Top Product
- Discover our top product BRK1 Primary Antibody
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anti-BRICK1, SCAR/WAVE Actin-Nucleating Complex Subunit (BRK1) antibody
BRK1 适用: 人, 小鼠 IHC, ELISA, WB 宿主: 兔 Polyclonal unconjugated
anti-BRICK1, SCAR/WAVE Actin-Nucleating Complex Subunit (BRK1) antibodyBRK1 适用: 人, 小鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-BRICK1, SCAR/WAVE Actin-Nucleating Complex Subunit (BRK1) (Middle Region) antibodyBRK1 适用: 人, 小鼠, 大鼠, 犬, 斑马鱼 IHC, WB 宿主: 兔 Polyclonal unconjugated
anti-BRICK1, SCAR/WAVE Actin-Nucleating Complex Subunit (BRK1) (C-Term) antibodyBRK1 适用: 人, 小鼠, 大鼠, 犬, 斑马鱼, Cow, 马, Pig, 猴, 非洲爪蟾 IHC, WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-BRICK1, SCAR/WAVE Actin-Nucleating Complex Subunit (BRK1) (Middle Region) antibodyBRK1 适用: 人, 小鼠, 大鼠, 犬, 斑马鱼, Cow, 马, Pig IHC, WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C for 12 months.
- 有效期
- 12 months
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- 抗原
- BRK1 (BRICK1, SCAR/WAVE Actin-Nucleating Complex Subunit (BRK1))
- 别名
- hHBrk1 (BRK1 产品)
- 别名
- brk1 antibody, C22H3orf10 antibody, brick1 antibody, c3orf10 antibody, C3orf10 antibody, MDS027 antibody, hHBrk1 antibody, 6720456B07Rik antibody, AW011779 antibody, ATBRK1 antibody, BRICK1 antibody, HSPC300 antibody, T9I22.8 antibody, T9I22_8 antibody, BRICK1, SCAR/WAVE actin-nucleating complex subunit antibody, BRICK1, SCAR/WAVE actin nucleating complex subunit antibody, brick 1 antibody, BRICK1, SCAR/WAVE actin-nucleating complex subunit S homeolog antibody, BRICK1 antibody, brk1 antibody, BRK1 antibody, Brk1 antibody, brk1.S antibody
- 背景
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Synonyms: Brk1-like, C3orf10 chromosome 3 open reading frame 10, C3ORF10 GENE, Chromosome 3 open reading frame 10, hHBrk1, HSPC300, MDS027, Probable protein BRICK1, BRK1_HUMAN.
Background: HSPC300 (hematopoietic stem cell protein 300) is also known as probable protein BRICK1 or C3orf10 (chromosome 3 open reading frame 10) and is a 75 amino acid protein that is expressed as two isoforms and localizes to both the cytoplasm and the cytoskeleton. HSPC300 is thought to regulate cytoskeletal organization and Actin polymerization. Free HSPC300 exists as homotrimers prior to its incorporation into the WAVE complex. The WAVE complex includes five proteins, one of which is HSPC300, that regulate the ARC (Arp2/3 complex) which is responsible for Actin nucleation and is Rac 1-dependent. Because HSPC300 is a highly conserved subunit of the WAVE complex across many species, it is thought to have the same or similar functions in many different organisms. In Drosophila, the WAVE/ARC pathway may affect the development of the nervous system. HSPC300 is thought to localize to axons of the central nervous system of Drosophila embryos and thus may also be involved in axonogenesis. In addition, HSPC300 is thought to be necessary for synaptic morphogenesis by motoneurons. In mice, the knockout of the WAVE complex leads to learning and memory defects, and it is therefore hypothesized that HSPC300 may also be involved in cognitive functions. Genetic depletion of HSPC300 results in cytoskeletal abnormalities and prevents cytokinesis of cells, suggesting that decreased levels of HSPC300 may be associated with tumor suppression.
- 基因ID
- 55845
- 途径
- RTK signaling
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