HSD3B7 抗体 (AA 131-197)
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- 抗原 See all HSD3B7 抗体
- HSD3B7 (Hydroxy-delta-5-Steroid Dehydrogenase, 3 beta- and Steroid delta-Isomerase 7 (HSD3B7))
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抗原表位
- AA 131-197
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This HSD3B7 antibody is un-conjugated
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应用范围
- ELISA, Western Blotting (WB), Immunofluorescence (IF)
- 交叉反应
- 人, 小鼠
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human 3 beta-hydroxysteroid dehydrogenase type 7 protein (131-197AA)
- 亚型
- IgG
- Top Product
- Discover our top product HSD3B7 Primary Antibody
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- 应用备注
- Recommended dilution: WB:1:500-1:5000, IF:1:50-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- HSD3B7 (Hydroxy-delta-5-Steroid Dehydrogenase, 3 beta- and Steroid delta-Isomerase 7 (HSD3B7))
- 别名
- HSD3B7 (HSD3B7 产品)
- 别名
- CBAS1 antibody, PFIC4 antibody, SDR11E3 antibody, AI195443 antibody, BB098564 antibody, Cca2 antibody, hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 antibody, HSD3B7 antibody, Hsd3b7 antibody
- 背景
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Background: The 3-beta-HSD enzymatic system plays a crucial role in the biosynthesis of all classes of hormonal steroids. HSD VII is active against four 7-alpha-hydroxylated sterols. Does not metabolize several different C(19/21) steroids as substrates. Involved in bile acid synthesis (PubMed:11067870). Plays a key role in cell positioning and movement in lymphoid tissues by mediating degradation of 7-alpha,25-dihydroxycholesterol (7-alpha,25-OHC): 7-alpha,25-OHC acts as a ligand for the G protein-coupled receptor GPR183/EBI2, a chemotactic receptor for a number of lymphoid cells.
Aliases: HSD3B73 beta-hydroxysteroid dehydrogenase type 7 antibody, 3 beta-hydroxysteroid dehydrogenase type VII antibody, 3-beta-HSD VII antibody, 3-beta-hydroxy-Delta(5)-C27 steroid oxidoreductase antibody, C(27) 3-beta-HSD antibody, EC 1.1.1.- antibody, Cholest-5-ene-3-beta,7-alpha-diol 3-beta-dehydrogenase antibody, EC 1.1.1.181 antibody
- UniProt
- Q9H2F3
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