MICAL1 抗体 (AA 806-1067) (HRP)
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- 抗原 See all MICAL1 抗体
- MICAL1 (Microtubule Associated Monoxygenase, Calponin and LIM Domain Containing 1 (MICAL1))
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抗原表位
- AA 806-1067
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MICAL1 antibody is conjugated to HRP
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应用范围
- ELISA
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human [F-actin]-methionine sulfoxide oxidase MICAL1 protein (806-1067AA)
- 亚型
- IgG
- Top Product
- Discover our top product MICAL1 Primary Antibody
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- MICAL1 (Microtubule Associated Monoxygenase, Calponin and LIM Domain Containing 1 (MICAL1))
- 别名
- MICAL1 (MICAL1 产品)
- 别名
- MICAL antibody, MICAL-1 antibody, NICAL antibody, Nical antibody, zgc:171928 antibody, microtubule associated monooxygenase, calponin and LIM domain containing 1 antibody, MICAL1 antibody, Mical1 antibody, mical1 antibody
- 背景
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Background: Monooxygenase that promotes depolymerization of F-actin by mediating oxidation of specific methionine residues on actin. Acts by modifying actin subunits through the addition of oxygen to form methionine-sulfoxide, leading to promote actin filament severing and prevent repolymerization (Probable). Acts as a cytoskeletal regulator that connects NEDD9 to intermediate filaments. Also acts as a negative regulator of apoptosis via its interaction with STK38 and STK38L, acts by antagonizing STK38 and STK38L activation by MST1/STK4. Involved in regulation of lamina-specific connectivity in the nervous system such as the development of lamina-restricted hippocampal connections. Through redox regulation of the actin cytoskeleton controls the intracellular distribution of sectrory vesicles containing L1/neurofascin/NgCAM family proteins in neurons, thereby regulating their cell surface levels (By similarity). May act as Rab effector protein and play a role in vesicle trafficking.
Aliases: CasL interacting molecule antibody, DKFZp434B1517 antibody, FLJ11937 antibody, FLJ21739 antibody, MICA1_HUMAN antibody, MICAL 1 antibody, MICAL antibody, MICAL1 antibody, microtubule associated monoxygenase, calponin and LIM domain containing 1 antibody, Molecule interacting with CasL protein 1 antibody, NEDD9 interacting protein with calponin homology and LIM domains antibody, NEDD9-interacting protein with calponin homology and LIM domains antibody, NICAL antibody, OTTHUMP00000016969 antibody
- UniProt
- Q8TDZ2
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