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UBE2O 抗体 (AA 10-277) (FITC)

UBE2O 适用: 人 宿主: 兔 Polyclonal FITC
产品编号 ABIN7141986
发货至: 中国
  • 抗原 See all UBE2O 抗体
    UBE2O (Ubiquitin-Conjugating Enzyme E2O (UBE2O))
    抗原表位
    • 15
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 10-277
    适用
    • 34
    • 6
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    宿主
    • 31
    • 2
    • 1
    克隆类型
    • 32
    • 2
    多克隆
    标记
    • 17
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This UBE2O antibody is conjugated to FITC
    应用范围
    请咨询
    交叉反应
    纯化方法
    Antigen Affinity Purified
    免疫原
    Recombinant Human (E3-independent) E2 ubiquitin-conjugating enzyme protein (10-277AA)
    亚型
    IgG
    Top Product
    Discover our top product UBE2O Primary Antibody
  • 限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    UBE2O (Ubiquitin-Conjugating Enzyme E2O (UBE2O))
    别名
    UBE2O (UBE2O 产品)
    别名
    e2-230k antibody, E2-230K antibody, 9630022H21 antibody, B230113M03Rik antibody, mKIAA1734 antibody, RGD1310297 antibody, ubiquitin conjugating enzyme E2 O antibody, ubiquitin-conjugating enzyme E2O antibody, UBE2O antibody, ube2o antibody, Ube2o antibody
    背景

    Background: E2/E3 hybrid ubiquitin-protein ligase that displays both E2 and E3 ligase activities and mediates monoubiquitination of target proteins (PubMed:23455153, PubMed:24703950). Negatively regulates TRAF6-mediated NF-kappa-B activation independently of its E2 activity (PubMed:23381138). Acts as a positive regulator of BMP7 signaling by mediating monoubiquitination of SMAD6, thereby regulating adipogenesis (PubMed:23455153). Mediates monoubiquitination at different sites of the nuclear localization signal (NLS) of BAP1, leading to cytoplasmic retention of BAP1. Also able to monoubiquitinate the NLS of other chromatin-associated proteins, such as INO80 and CXXC1, affecting their subcellular location (PubMed:24703950). Acts as a regulator of retrograde transport by assisting the TRIM27:MAGEL2 E3 ubiquitin ligase complex to mediate \\\'Lys-63\\\'-linked ubiquitination of WASH1, leading to promote endosomal F-actin assembly (PubMed:23452853).

    Aliases: E2 230K antibody, EC=6.3.2.19 antibody, FLJ12878 antibody, KIAA1734 antibody, Likely Ortholog of Mouse Ubiquitin Conjugating Enzyme antibody, RP23 193A16.5 antibody, UBE2O antibody, UBE2O_HUMAN antibody, Ubiquitin carrier protein O antibody, Ubiquitin conjugating enzyme E2 O antibody, Ubiquitin conjugating enzyme E2 of 230 kDa antibody, ubiquitin conjugating enzyme E2O antibody, Ubiquitin protein ligase O antibody, Ubiquitin-conjugating enzyme E2 O antibody, Ubiquitin-conjugating enzyme E2 of 230 kDa antibody, Ubiquitin-conjugating enzyme E2-230K antibody, Ubiquitin-protein ligase O antibody

    UniProt
    Q9C0C9
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