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CD14 抗体

CD14 适用: 人 IHC, ELISA 宿主: 小鼠 Monoclonal 1A3B6 unconjugated
产品编号 ABIN7140933
发货至: 中国
  • 抗原 See all CD14 抗体
    CD14
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    小鼠
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    单克隆
    标记
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    This CD14 antibody is un-conjugated
    应用范围
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    Immunohistochemistry (IHC), ELISA
    交叉反应
    纯化方法
    Protein G purified
    免疫原
    Recombinant CD14 Protein
    克隆位点
    1A3B6
    亚型
    IgG2b
    Top Product
    Discover our top product CD14 Primary Antibody
  • 应用备注
    Recommended dilution:IHC:1:50-1:500,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    CD14
    别名
    CD14 (CD14 产品)
    别名
    CD14 molecule antibody, CD14 antigen antibody, CD14 antibody, Cd14 antibody
    背景

    Background: As a component of the innate immune system, the cell surface glycoprotein CD14 is a myelomonocytic differentiation antigen preferentially expressed on monocytes, macrophages, and activated granulocytes. CD14 exists as two forms, either anchored into the membrane by a GPI-anchor tail (mCD14) or present as a soluble form (sCD14) in normal serum and body fluids. CD14 was first described as a pattern recognition receptor for lipopolysaccharide (LPS) and a variety of ligands derived from different microbial sources, along with the co-receptors Toll-like receptor TLR 4 and MD-2. The binding of CD14 and LPS depends on the presence and catalytic activity of lipopolysaccharide-binding protein (LBP). Besides its endotoxin signaling function, CD14 has been proposed to be involved in various biological processes, including transportation of other lipids, cell-cell interaction during different immune responses, as well as recognition of apoptotic cells. Multiple transcript variants resulting from alternative splicing encode the same isoform of CD14.

    Aliases: CD14, CD14 Molecule

    UniProt
    P08571
    途径
    TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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