SIGMAR1 抗体 (AA 21-120)
-
- 抗原 See all SIGMAR1 抗体
- SIGMAR1 (sigma Non-Opioid Intracellular Receptor 1 (SIGMAR1))
-
抗原表位
- AA 21-120
- 适用
- 人, 小鼠, 大鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This SIGMAR1 antibody is un-conjugated
- 应用范围
- Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 交叉反应
- 人, 小鼠, 大鼠
- 预测反应
- Dog,Cow,Pig,Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human OPRS1
- 亚型
- IgG
- Top Product
- Discover our top product SIGMAR1 Primary Antibody
-
-
- 应用备注
-
WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 - 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
-
- 抗原
- SIGMAR1 (sigma Non-Opioid Intracellular Receptor 1 (SIGMAR1))
- 别名
- OPRS1 (SIGMAR1 产品)
- 别名
- ALS16 antibody, OPRS1 antibody, SIG-1R antibody, SR-BP antibody, SR-BP1 antibody, SRBP antibody, sigma1R antibody, AL024364 antibody, Oprs1 antibody, mSigmaR1 antibody, Sigma1R antibody, oprs1 antibody, zgc:56378 antibody, sigma non-opioid intracellular receptor 1 antibody, sigma non-opioid intracellular receptor 1 L homeolog antibody, SIGMAR1 antibody, Sigmar1 antibody, sigmar1.L antibody, sigmar1 antibody
- 背景
-
Synonyms: SRBP, ALS16, OPRS1, SR-BP, SIG-1R, SR-BP1, sigma1R, hSigmaR1, Sigma non-opioid intracellular receptor 1, Aging-associated gene 8 protein, SR31747-binding protein, Sigma 1-type opioid receptor, Sigma1-receptor, SIGMAR1, AAG8
Background: Functions in lipid transport from the endoplasmic reticulum and is involved in a wide array of cellular functions probably through regulation of the biogenesis of lipid microdomains at the plasma membrane. Involved in the regulation of different receptors it plays a role in BDNF signaling and EGF signaling. Also regulates ion channels like the potassium channel and could modulate neurotransmitter release. Plays a role in calcium signaling through modulation together with ANK2 of the ITP3R-dependent calcium efflux at the endoplasmic reticulum. Plays a role in several other cell functions including proliferation, survival and death. Originally identified for its ability to bind various psychoactive drugs it is involved in learning processes, memory and mood alteration.
- 基因ID
- 10280
- UniProt
- Q99720
- 途径
- SARS-CoV-2 Protein Interactome
-