BRAP 抗体
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- 抗原 See all BRAP 抗体
- BRAP (BRCA1 Associated Protein (BRAP))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This BRAP antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 交叉反应
- 人
- 纯化方法
- Affinity purified
- 免疫原
- Purified recombinant human BRAP protein fragments expressed in E.coli.
- 亚型
- IgG1, IgG1 kappa
- Top Product
- Discover our top product BRAP Primary Antibody
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- 应用备注
- Recommended dilution:WB:1:500-1:5000,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified mouse monoclonal antibody in PBS( pH 7.4) containing with 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- BRAP (BRCA1 Associated Protein (BRAP))
- 别名
- BRAP (BRAP 产品)
- 别名
- imp antibody, MGC68778 antibody, zgc:92894 antibody, BRAP antibody, BRAP2 antibody, IMP antibody, RNF52 antibody, 3010002G07Rik antibody, BRCA1 associated protein S homeolog antibody, BRCA1 associated protein antibody, BRCA1-associated protein antibody, brca1-associated protein antibody, brap.S antibody, brap antibody, BRAP antibody, NAEGRDRAFT_81654 antibody, CC1G_00971 antibody, CpipJ_CPIJ003557 antibody, Tsp_05101 antibody, LOC100282389 antibody, Brap antibody
- 背景
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Background: Negatively regulates MAP kinase activation by limiting the formation of Raf/MEK complexes probably by inactivation of the KSR1 scaffold protein. Also acts as a Ras responsive E3 ubiquitin ligase that, on activation of Ras, is modified by auto-polyubiquitination resulting in the release of inhibition of Raf/MEK complex formation. May also act as a cytoplasmic retention protein with a role in regulating nuclear transport.
Aliases: 3010002G07Rik, BRAP2, BRCA1 associated protein, EC 6.3.2., Galectin 2 binding protein, IMP, Impedes mitogenic signal propagation, Renal carcinoma antigen NY REN 63, RING finger protein 52, RNF52, zgc:92894.
- UniProt
- Q7Z569
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