INPP5F 抗体 (AA 187-204) (HRP)
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- 抗原 See all INPP5F 抗体
- INPP5F (Inositol Polyphosphate-5-Phosphatase F (INPP5F))
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抗原表位
- AA 187-204
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This INPP5F antibody is conjugated to HRP
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应用范围
- ELISA
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Peptide sequence from Human Phosphatidylinositide phosphatase SAC2 protein (187-204AA)
- 亚型
- IgG
- Top Product
- Discover our top product INPP5F Primary Antibody
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- INPP5F (Inositol Polyphosphate-5-Phosphatase F (INPP5F))
- 别名
- INPP5F (INPP5F 产品)
- 别名
- MSTPO47 antibody, SAC2 antibody, hSAC2 antibody, 5830435P03Rik antibody, AI115354 antibody, AW561896 antibody, cI-27 antibody, mKIAA0966 antibody, im:7143897 antibody, si:dkey-192p21.1 antibody, inositol polyphosphate-5-phosphatase F antibody, INPP5F antibody, Inpp5f antibody, inpp5f antibody
- 背景
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Background: Inositol 4-phosphatase which mainly acts on phosphatidylinositol 4-phosphate. May be functionally linked to OCRL, which converts phosphatidylinositol 4,5-bisphosphate to phosphatidylinositol, for a sequential dephosphorylation of phosphatidylinositol 4,5-bisphosphate at the 5 and 4 position of inositol, thus playing an important role in the endocytic recycling (PubMed:25869669). Regulator of TF:TFRC and integrins recycling pathway, is also involved in cell migration mechanisms (PubMed:25869669). Modulates AKT/GSK3B pathway by decreasing AKT and GSK3B phosphorylation (PubMed:17322895). Negatively regulates STAT3 signaling pathway through inhibition of STAT3 phosphorylation and translocation to the nucleus (PubMed:25476455). Functionally important modulator of cardiac myocyte size and of the cardiac response to stress (By similarity). May play a role as negative regulator of axon regeneration after central nervous system injuries (By similarity).
Aliases: INPP5F antibody, KIAA0966 antibody, SAC2 antibody, MSTP007 antibody, MSTP047 antibody, Phosphatidylinositide phosphatase SAC2 antibody, EC 3.1.3.25 antibody, Inositol polyphosphate 5-phosphatase F antibody, Sac domain-containing inositol phosphatase 2 antibody, Sac domain-containing phosphoinositide 4-phosphatase 2 antibody, hSAC2 antibody
- UniProt
- Q9Y2H2
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