MDFIC 抗体 (AA 35-53)
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- 抗原 See all MDFIC 抗体
- MDFIC (MyoD Family Inhibitor Domain Containing (MDFIC))
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抗原表位
- AA 35-53
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MDFIC antibody is un-conjugated
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应用范围
- ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Peptide sequence from Human MyoD family inhibitor domain-containing protein (35-53AA)
- 亚型
- IgG
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- 应用备注
- Recommended dilution: IHC:1:200-1:500, IF:1:50-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- MDFIC (MyoD Family Inhibitor Domain Containing (MDFIC))
- 别名
- MDFIC (MDFIC 产品)
- 别名
- HIC antibody, Kdt1 antibody, Mdfid antibody, MyoD family inhibitor domain containing antibody, MyoD family inhibitor domain containing S homeolog antibody, MDFIC antibody, Mdfic antibody, mdfic.S antibody
- 背景
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Background: Acts as a transcriptional activator or repressor. Inhibits the transcriptional activation of Zic family proteins ZIC1, ZIC2 and ZIC3. Retains nuclear Zic proteins ZIC1, ZIC2 and ZIC3 in the cytoplasm. Modulates the expression from both cellular and viral promoters. Down-regulates Tat-dependent transcription of the human immunodeficiency virus type 1 (HIV-1) LTR by interacting with HIV-1 Tat and Rev and impairing their nuclear import, probably by rendering the NLS domains inaccessible to importin-beta. Also stimulates activation of human T-cell leukemia virus type I (HTLV-I) LTR. Binds to the axin complex, resulting in an increase in the level of free beta-catenin. Affects axin regulation of the WNT and JNK signaling pathways.
Aliases: MDFIC antibody, MyoD family inhibitor domain-containing protein antibody, I-mfa domain-containing protein antibody, hIC antibody
- UniProt
- Q9P1T7
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