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IgG3 抗体 (AA 312-324) (HRP)

适用: 人 ELISA 宿主: 兔 Polyclonal HRP
产品编号 ABIN7139886
发货至: 中国
  • 抗原 See all IgG3 抗体
    IgG3
    抗原表位
    • 3
    • 1
    AA 312-324
    适用
    宿主
    • 4
    • 1
    克隆类型
    • 4
    • 1
    多克隆
    标记
    • 3
    • 1
    • 1
    This IgG3 antibody is conjugated to HRP
    应用范围
    • 3
    • 2
    ELISA
    交叉反应
    纯化方法
    >95%, Protein G purified
    免疫原
    Peptide sequence from Human Immunoglobulin heavy constant gamma 3 protein (312-324AA)
    亚型
    IgG
    Top Product
    Discover our top product IgG3 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    IgG3
    别名
    IGHG3 (IgG3 产品)
    别名
    IgG3 antibody, Immunoglobulin heavy constant gamma 3 antibody, immunoglobulin heavy constant gamma 3 (G3m marker) antibody, Ighg3 antibody, IGHG3 antibody
    物质类
    Antibody
    背景

    Background: Constant region of immunoglobulin heavy chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:22158414, PubMed:20176268). The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed:17576170, PubMed:20176268).

    Aliases: IGHG3Immunoglobulin heavy constant gamma 3 antibody, HDC antibody, Heavy chain disease protein antibody, Ig gamma-3 chain C region antibody

    UniProt
    P01860
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