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Cofilin1/2 (CFL1/2) (pTyr88) 抗体

CFL1/2 适用: 人 IHC, WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7139084
发货至: 中国
  • 抗原 See all Cofilin1/2 (CFL1/2) 抗体
    Cofilin1/2 (CFL1/2)
    抗原表位
    • 10
    • 2
    • 1
    pTyr88
    适用
    • 13
    • 12
    • 9
    宿主
    • 13
    克隆类型
    • 13
    多克隆
    标记
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    非结合性
    应用范围
    • 5
    • 4
    • 3
    • 3
    • 1
    Immunohistochemistry (IHC), Western Blotting (WB), ELISA
    交叉反应
    人, 小鼠
    纯化方法
    Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
    免疫原
    Peptide sequence around phosphorylation site of tyrosine 88 (A-T-Y(p)-E-T) derived from Human coflin1/cofilin2.
    亚型
    IgG
  • 应用备注
    WB:1:500-1:1000, IHC:1:50-1:100,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    Cofilin1/2 (CFL1/2)
    别名
    CFL1/CFL2 (CFL1/2 产品)
    别名
    CFL antibody, cofilin 1 antibody, CFL1 antibody
    背景

    Background: Controls reversibly actin polymerization and depolymerization in a pH -sensitive manner. It has the ability to bind G- and F-actin in a 1:1 ratio of cofilin to actin. It is the major component of intranuclear and cytoplasmic actin rods.

    Carlier, M. et al. (1999) J. Biol. Chem. 274, 33827-33830.
    Arber, S. et al. (1998) Nature 393, 805-809.
    Yang, N. et al. (1998) Nature 393, 809-812.

    Aliases: CFL1/CFL2

    UniProt
    P23528, Q9Y281
    途径
    Tube Formation, CXCR4-mediated Signaling Events
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