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EPH Receptor A7 抗体 (pTyr791)

EPHA7 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7139071
发货至: 中国
  • 抗原 See all EPH Receptor A7 (EPHA7) 抗体
    EPH Receptor A7 (EPHA7)
    抗原表位
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    pTyr791
    适用
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    宿主
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    克隆类型
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    多克隆
    标记
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    This EPH Receptor A7 antibody is un-conjugated
    应用范围
    • 50
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    Western Blotting (WB), ELISA
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
    免疫原
    Peptide sequence around phosphorylation site of tyrosine 791 (A-V-Y(p)-T-T) derived from Human EPHA7 .
    亚型
    IgG
    Top Product
    Discover our top product EPHA7 Primary Antibody
  • 应用备注
    WB:1:500-1:1000,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    EPH Receptor A7 (EPHA7)
    别名
    EPHA7 (EPHA7 产品)
    别名
    fc51g03 antibody, wu:fc51g03 antibody, si:dkey-23k6.1 antibody, EHK3 antibody, HEK11 antibody, Cek11 antibody, Ebk antibody, Ehk3 antibody, Hek11 antibody, Mdk1 antibody, CEPHA7 antibody, EPH receptor A7 antibody, eph receptor A7 antibody, ephrin type-B receptor 1-B antibody, Eph receptor A7 antibody, EPHA7 antibody, epha7 antibody, LOC100166161 antibody, Epha7 antibody
    背景

    Background:

    Receptor tyrosine kinase which binds promiscuously GPI-anchored ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Among GPI-anchored ephrin-A ligands, EFNA5 is a cognate/functional ligand for EPHA7 and their interaction regulates brain development modulating cell-cell adhesion and repulsion. Has a repellent activity on axons and is for instance involved in the guidance of corticothalamic axons and in the proper topographic mapping of retinal axons to the colliculus.

    Fox G.M., Oncogene 10:897-905(1995).
    Mungall A.J., Nature 425:805-811(2003).

    Aliases: Cek 11 antibody, Developmental kinase 1 antibody, EBK antibody, EHK-3 antibody, EHK3 antibody, EK11 antibody, Embryonic brain kinase antibody, EPH homology kinase 3 antibody, EPH-like kinase 11 antibody, Epha7 antibody, EPHA7_HUMAN antibody, Ephrin receptor Eph A7 antibody, Ephrin type A receptor 7 antibody, Ephrin type-A receptor 7 antibody, hEK11 antibody, MDK 1 antibody, Receptor protein tyrosine kinase HEK 11 antibody, Tyrosine protein kinase receptor EHK 3 antibody

    UniProt
    Q15375
    途径
    RTK signaling
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