CSF1R 抗体 (pTyr561)
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- 抗原 See all CSF1R 抗体
- CSF1R (Colony Stimulating Factor 1 Receptor (CSF1R))
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抗原表位
- pTyr561
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CSF1R antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- 交叉反应
- 人, 小鼠
- 纯化方法
- Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
- 免疫原
- Peptide sequence around phosphorylation site of tyrosine 561 (N-S-Y(p)-T-F) derived from Human CSFR .
- 亚型
- IgG
- Top Product
- Discover our top product CSF1R Primary Antibody
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- 应用备注
- WB:1:500-1:1000, IHC:1:50-1:100,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- CSF1R (Colony Stimulating Factor 1 Receptor (CSF1R))
- 别名
- CSF1R (CSF1R 产品)
- 别名
- AI323359 antibody, CD115 antibody, CSF-1R antibody, Csfmr antibody, Fim-2 antibody, Fms antibody, M-CSF-R antibody, M-CSFR antibody, C-FMS antibody, CSFR antibody, FIM2 antibody, FMS antibody, HDLS antibody, PDGFRB antibody, MGC89146 antibody, CSF-1-R antibody, c-fms antibody, mrfms antibody, CSF1 antibody, M-CSF antibody, csf1r antibody, fms antibody, panther antibody, colony stimulating factor 1 receptor antibody, macrophage colony-stimulating factor receptor antibody, colony stimulating factor 1 receptor, a antibody, Csf1r antibody, CSF1R antibody, m-csfr antibody, csf1r antibody, csf1ra antibody
- 背景
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Background:
Tyrosine-protein kinase that acts as cell-surface receptor for CSF1 and IL34 and plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines in response to IL34 and CSF1, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone and tooth development.
Hampe A., Oncogene Res. 4:9-17(1989).
Andre C., Genomics 39:216-226(1997).
Liu T., J. Proteome Res. 4:2070-2080(2005).Aliases: C FMS antibody, CD 115 antibody, CD115 antibody, CD115 antigen antibody, CFMS antibody, Colony stimulating factor 1 receptor antibody, Colony stimulating factor I receptor antibody, CSF 1 R antibody, CSF 1R antibody, CSF-1 receptor antibody, CSF-1-R antibody, CSF1 R antibody, CSF1R antibody, CSF1R_HUMAN antibody, CSFR antibody, EC 2.7.10.1 antibody, FIM 2 antibody, FIM2 antibody, FMS antibody, FMS proto oncogene antibody, FMS protooncogene antibody, HDLS antibody, M-CSF Receptor antibody, M-CSF-R antibody, Macrophage colony stimulating factor 1 receptor antibody, Macrophage colony stimulating factor I receptor antibody, Macrophage colony-stimulating factor 1 receptor antibody, McDonough feline sarcoma viral (v fms) oncogene homolog antibody, MCSFR antibody, Oncogen FMS antibody, Proto-oncogene c-Fms antibody, V-FMS McDonough feline sarcoma viral oncogen homolog, formerly antibody
- UniProt
- P07333
- 途径
- RTK signaling, Inositol Metabolic Process, Cell-Cell Junction Organization
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