Src 抗体 (pTyr529)
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- 抗原 See all Src 抗体
- Src (Proto-oncogene tyrosine-protein kinase Src (Src))
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抗原表位
- pTyr529
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Src antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
- 免疫原
- Peptide sequence around phosphorylation site of tyrosine 529 (P-Q-Y(p)-Q-P) derived from Human Src.
- 亚型
- IgG
- Top Product
- Discover our top product Src Primary Antibody
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- 应用备注
- WB:1:500-1:1000, IHC:1:50-1:100, IF:1:100-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- Src (Proto-oncogene tyrosine-protein kinase Src (Src))
- 别名
- SRC (Src 产品)
- 别名
- AW259666 antibody, pp60c-src antibody, C-src1 antibody, CG7524 antibody, D-Src64B antibody, D-src antibody, DSRC64 antibody, DSrc antibody, DSrc64 antibody, DSrc64B antibody, Dm SRC1 antibody, DmHD-358 antibody, Dmel\CG7524 antibody, Dsrc antibody, Dsrc64 antibody, Dsrc64B antibody, HD-358 antibody, MRE5 antibody, SRC 64B antibody, Src antibody, Src1 antibody, Src64 antibody, c-src antibody, dSrc antibody, dsrc antibody, src antibody, src1 antibody, src64 antibody, src64B antibody, src64b antibody, ASV antibody, SRC1 antibody, c-SRC antibody, p60-Src antibody, c-Src antibody, PP60C-SCR antibody, SDR antibody, SRC proto-oncogene, non-receptor tyrosine kinase antibody, uncharacterized LOC5574802 antibody, proto-oncogene tyrosine-protein kinase src antibody, Rous sarcoma oncogene antibody, Src oncogene at 64B antibody, SRC antibody, LOC5574802 antibody, CpipJ_CPIJ010659 antibody, Src antibody, Src64B antibody
- 物质类
- Viral Protein
- 背景
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Background:
proto-oncogenic cytoplasmic tyrosine kinase of the SRC family. Highly expressed in certain fully differentiated cells such as neurons, platelets and macrophages. Phosphorylation of an activation loop tyrosine activates the enzyme, phosphorylation of a tyrosine in the C-terminus by Csk inhibits the enzyme.
Pyper J.M., (1985) Mol. Cell. Biol. 5:831-838
Pyper J.M.(1990) Mol. Cell. Biol. 10:2035-2040
Xu W., (1997).Nature 385:595-602
Benes C.H., (2005) Cell 121:271-280Aliases: ASV antibody, Avian sarcoma virus antibody, AW259666 antibody, c SRC antibody, CDNA FLJ14219 fis clone NT2RP3003800 highly similar to Rattus norvegicus tyrosine protein kinase pp60 c src mRNA antibody, cSrc antibody, EC 2.7.10.2 antibody, Neuronal CSRC tyrosine specific protein kinase antibody, Neuronal proto-oncogene tyrosine-protein kinase Src antibody, Neuronal SRC antibody, Oncogene SRC antibody, OTTHUMP00000174476 antibody, OTTHUMP00000174477 antibody, p60 Src antibody, p60-Src antibody, p60c-src antibody, p60Src antibody, pp60c src antibody, pp60c-src antibody, pp60csrc antibody, Proto oncogene tyrosine protein kinase Src antibody, Proto-oncogene c-Src antibody, Proto-oncogene tyrosine-protein kinase Src antibody, Protooncogene SRC antibody, Protooncogene SRC Rous sarcoma antibody, Src antibody, SRC Oncogene antibody, SRC proto oncogene non receptor tyrosine kinase antibody, SRC_HUMAN antibody, SRC1 antibody, Tyrosine kinase pp60c src antibody, Tyrosine protein kinase SRC 1 antibody, Tyrosine protein kinase SRC1 antibody, v src avian sarcoma (Schmidt Ruppin A2) viral oncogene homolog antibody, V src sarcoma (Schmidt Ruppin A 2) viral oncogene homolog (avian) antibody, v src sarcoma (Schmidt Ruppin A 2) viral oncogene homolog avian antibody
- UniProt
- P12931
- 途径
- JAK/STAT Signaling, Neurotrophin Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Cellular Response to Molecule of Bacterial Origin, Cell-Cell Junction Organization, Regulation of Carbohydrate Metabolic Process, Autophagy, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Negative Regulation of intrinsic apoptotic Signaling, Platelet-derived growth Factor Receptor Signaling, Thromboxane A2 Receptor Signaling, Signaling of Hepatocyte Growth Factor Receptor, VEGF Signaling
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