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HCK 抗体 (pTyr521)

HCK 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7139019
发货至: 中国
  • 抗原 See all HCK 抗体
    HCK (Hemopoietic Cell Kinase (HCK))
    抗原表位
    • 16
    • 15
    • 10
    • 7
    • 6
    • 6
    • 6
    • 6
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pTyr521
    适用
    • 90
    • 32
    • 21
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 82
    • 8
    • 1
    克隆类型
    • 85
    • 6
    多克隆
    标记
    • 45
    • 7
    • 6
    • 6
    • 5
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This HCK antibody is un-conjugated
    应用范围
    • 73
    • 50
    • 23
    • 14
    • 14
    • 13
    • 12
    • 8
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
    免疫原
    Peptide sequence around phosphorylation site of tyrosine 521(E-S-Q(p)-Y-Q) derived from Human HCK .
    亚型
    IgG
    Top Product
    Discover our top product HCK Primary Antibody
  • 应用备注
    WB:1:500-1:1000,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    HCK (Hemopoietic Cell Kinase (HCK))
    别名
    HCK (HCK 产品)
    别名
    laloo antibody, HCK antibody, MGC107870 antibody, JTK9 antibody, p59Hck antibody, p61Hck antibody, AI849071 antibody, Bmk antibody, Hctk antibody, p56Hck antibody, HCK proto-oncogene, Src family tyrosine kinase L homeolog antibody, HCK proto-oncogene, Src family tyrosine kinase antibody, hemopoietic cell kinase antibody, hck.L antibody, HCK antibody, hck antibody, Hck antibody
    背景

    Background:

    The protein encoded by this gene is a protein-tyrosine kinase that is predominantly expressed in hemopoietic cell types. The encoded protein may help couple the Fc receptor to the activation of the respiratory burst. In addition, it may play a role in neutrophil migration and in the degranulation of neutrophils. Alternate translation initiation site usage, including a non-AUG (CUG) codon, results in the production of two different isoforms, that have different subcellular localization.

    Quintrell N., Mol. Cell. Biol. 7:2267-2275(1987) [PubMed: 3496523].
    Ziegler S.F.,Mol. Cell. Biol. 7:2276-2285(1987) [PubMed: 3453117].
    Ota T., Nat. Genet. 36:40-45(2004) [PubMed: 14702039].

    Aliases: Bmk antibody, Hck 1 antibody, Hck antibody, HCK_HUMAN antibody, Hemopoietic cell kinase antibody, JTK9 antibody, p59-HCK/p60-HCK antibody, p59Hck antibody, p59HCK/p60HCK antibody, p61Hck antibody, Tyrosine protein kinase HCK antibody, Tyrosine-protein kinase HCK antibody

    UniProt
    P08631
    途径
    Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling
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