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BLK 抗体 (pTyr501)

BLK 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7139015
发货至: 中国
  • 抗原 See all BLK 抗体
    BLK (B Lymphoid Tyrosine Kinase (BLK))
    抗原表位
    • 15
    • 13
    • 9
    • 7
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pTyr501
    适用
    • 66
    • 24
    • 15
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 53
    • 10
    • 1
    克隆类型
    • 55
    • 11
    多克隆
    标记
    • 35
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This BLK antibody is un-conjugated
    应用范围
    • 51
    • 37
    • 28
    • 13
    • 13
    • 8
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    ELISA, Immunohistochemistry (IHC)
    交叉反应
    人, 小鼠
    纯化方法
    Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
    免疫原
    Peptide sequence around phosphorylation site of tyrosine 501 (R-Q-Y(p)-E-L) derived from Human BLK.
    亚型
    IgG
    Top Product
    Discover our top product BLK Primary Antibody
  • 应用备注
    IHC:1:50-1:100,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    BLK (B Lymphoid Tyrosine Kinase (BLK))
    别名
    BLK (BLK 产品)
    别名
    bltk antibody, si:dkey-33i22.2 antibody, zgc:136231 antibody, MODY11 antibody, BLK proto-oncogene, Src family tyrosine kinase antibody, B lymphoid kinase antibody, blk antibody, BLK antibody, Blk antibody
    背景

    Background:

    Non-receptor tyrosine kinase involved in B-lymphocyte development, differentiation and signaling. B-cell receptor (BCR) signaling requires a tight regulation of several protein tyrosine kinases and phosphatases, and associated coreceptors. Binding of antigen to the B-cell antigen receptor (BCR) triggers signaling that ultimately leads to B-cell activation. Signaling through BLK plays an important role in transmitting signals through surface immunoglobulins and supports the pro-B to pre-B transition, as well as the signaling for growth arrest and apoptosis downstream of B-cell receptor.

    Islam K.B., J. Immunol. 154:1265-1272(1995).
    Drebin J.A.,Oncogene 10:477-486(1995).
    Greenman C.,Nature 446:153-158(2007).

    Aliases: B lymphocyte kinase antibody, B lymphoid tyrosine kinase antibody, Blk antibody, BLK nonreceptor tyrosine kinase antibody, BLK_HUMAN antibody, EC 2.7.10.2 antibody, MGC 10442 antibody, MGC10442 antibody, MODY 11 antibody, MODY11 antibody, P55 BLK antibody, p55-BLK antibody, Tyrosine kinase B lymphocyte specific antibody, Tyrosine protein kinase antibody, Tyrosine-protein kinase BLK antibody

    UniProt
    P51451
    途径
    Positive Regulation of Peptide Hormone Secretion, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling
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