BLM 抗体 (pThr99)
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- 抗原 See all BLM 抗体
- BLM (Bloom Syndrome RecQ Like Helicase (BLM))
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抗原表位
- pThr99
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This BLM antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- 交叉反应
- 人
- 纯化方法
- Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
- 免疫原
- Peptide sequence around phosphorylation site of threonine 99 (Q-E-T(p)-Q-R) derived from Human Bloom Syndrome.
- 亚型
- IgG
- Top Product
- Discover our top product BLM Primary Antibody
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- 应用备注
- WB:1:500-1:1000, IHC:1:50-1:100,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- BLM (Bloom Syndrome RecQ Like Helicase (BLM))
- 别名
- BLM (BLM 产品)
- 别名
- BS antibody, RECQ2 antibody, RECQL2 antibody, RECQL3 antibody, blm-A antibody, xBLM antibody, ORF1 antibody, Bloom syndrome RecQ like helicase antibody, Bloom syndrome RecQ like helicase S homeolog antibody, Bloom syndrome, RecQ like helicase antibody, BLM antibody, blm.S antibody, Blm antibody
- 背景
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Background:
Participates in DNA replication and repair. Exhibits a magnesium-dependent ATP-dependent DNA-helicase activity that unwinds single- and double-stranded DNA in a 3'-5' direction. Involved in 5'-end resection of DNA during double-strand break (DSB) repair: unwinds DNA and recruits DNA2 which mediates the cleavage of 5'-ssDNA. Negatively regulates sister chromatid exchange (SCE).
Ellis N.A., Cell 83:655-666(1995).
Karow J.K., J. Biol. Chem. 272:30611-30614(1997).
Pichierri P., EMBO J. 23:3154-3163(2004).Aliases: Blm antibody, BLM_HUMAN antibody, Bloom syndrome antibody, Bloom syndrome protein antibody, Bloom syndrome RecQ helicase like antibody, BS antibody, DNA helicase antibody, DNA helicase RecQ like type 2 antibody, MGC126616 antibody, MGC131618 antibody, MGC131620 antibody, RECQ 2 antibody, RECQ like antibody, RecQ like type 2 antibody, RecQ protein like 3 antibody, RecQ protein-like 3 antibody, RecQ-like type 2 antibody, RecQ2 antibody, RECQL 2 antibody, RECQL 3 antibody, RECQL2 antibody, RECQL3 antibody, type 2 antibody
- UniProt
- P54132
- 途径
- DNA Damage Repair
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