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- 抗原 See all RPS6KA1 抗体
- RPS6KA1 (Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 1 (RPS6KA1))
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抗原表位
- pThr573
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This RPS6KA1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
- 免疫原
- Peptide sequence around phosphorylation site of threonine 573(L-M-T(p)-P-C) derived from Human p90 RSK.
- 亚型
- IgG
- Top Product
- Discover our top product RPS6KA1 Primary Antibody
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anti-Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 1 (RPS6KA1) (AA 62-321) antibody
RPS6KA1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 1 (RPS6KA1) (AA 1-735) antibodyRPS6KA1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4E11 unconjugated
anti-Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 1 (RPS6KA1) (C-Term) antibodyRPS6KA1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 1 (RPS6KA1) (Thr573) antibodyRPS6KA1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 1 (RPS6KA1) (pSer363), (pThr359) antibodyRPS6KA1 适用: 人 WB, ELISA, IP, IF 宿主: 兔 Monoclonal 1B6 unconjugated Recombinant Antibody
anti-Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 1 (RPS6KA1) (pSer363), (pThr359) antibodyRPS6KA1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 1 (RPS6KA1) (AA 539-588) antibodyRPS6KA1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 1 (RPS6KA1) (C-Term) antibodyRPS6KA1 适用: 人 WB, ELISA, IP, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 1 (RPS6KA1) (C-Term) antibody (FITC)RPS6KA1 适用: 人 WB, ELISA, IP, IF, ICC 宿主: 兔 Polyclonal FITC
anti-Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 1 (RPS6KA1) (C-Term) antibody (Biotin)RPS6KA1 适用: 人 WB, ELISA, IP, IF, ICC 宿主: 兔 Polyclonal Biotin
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- 应用备注
- WB:1:500-1:1000, IHC:1:50-1:100,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- RPS6KA1 (Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 1 (RPS6KA1))
- 别名
- RPS6KA1 (RPS6KA1 产品)
- 别名
- HU-1 antibody, MAPKAPK1A antibody, RSK antibody, RSK1 antibody, Rsk1 antibody, p90rsk antibody, rsk antibody, RPS6KA antibody, hu-1 antibody, mapkapk1a antibody, rsk1 antibody, wu:fc56h07 antibody, zgc:152654 antibody, ribosomal protein S6 kinase A1 antibody, ribosomal protein S6 kinase polypeptide 1 antibody, ribosomal protein S6 kinase A1-like antibody, ribosomal protein S6 kinase A1 L homeolog antibody, ribosomal protein S6 kinase a, polypeptide 1 antibody, RPS6KA1 antibody, Rps6ka1 antibody, RPS6KA1L antibody, rps6ka1.L antibody, rps6ka1 antibody
- 背景
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Background:
Serine/threonine-protein kinase that acts downstream of ERK (MAPK1/ERK2 and MAPK3/ERK1) signaling and mediates mitogenic and stress-induced activation of the transcription factors CREB1, ETV1/ER81 and NR4A1/NUR77, regulates translation through RPS6 and EIF4B phosphorylation, and mediates cellular proliferation, survival, and differentiation by modulating mTOR signaling and repressing pro-apoptotic function of BAD and DAPK1. In fibroblast, is required for EGF-stimulated phosphorylation of CREB1, which results in the subsequent transcriptional activation of several immediate-early genes.
Eiichi Takahashi, J. Biol. Chem., Jul 1999, 274: 20206.
Ye Zhang, J. Biol. Chem., May 2002, 277: 19042 - 19048.
Ganesh R. Panta, Mol. Cell. Biol., Mar 2004, 24: 1823 - 1835.Aliases: 90 kDa ribosomal protein S6 kinase 1 antibody, dJ590P13.1 (ribosomal protein S6 kinase, 90kD, polypeptide 1 antibody, dJ590P13.1 antibody, EC 2.7.11.1 antibody, HU 1 antibody, HU1 antibody, KS6A1_HUMAN antibody, MAP kinase activated protein kinase 1a antibody, MAP kinase-activated protein kinase 1a antibody, MAPK-activated protein kinase 1a antibody, MAPKAP kinase 1a antibody, MAPKAPK-1a antibody, MAPKAPK1A antibody, MGC79981 antibody, Mitogen-activated protein kinase-activated protein kinase 1A antibody, OTTHUMP00000004113 antibody, p90 RSK1 antibody, p90-RSK 1 antibody, p90rsk antibody, p90RSK1 antibody, p90S6K antibody, pp90RSK1 antibody, Ribosomal protein S6 kinase 90kD 1 antibody, Ribosomal protein S6 kinase 90kD polypeptide 1 antibody, Ribosomal protein S6 kinase 90 kDa polypeptide 1 antibody, Ribosomal protein S6 kinase alpha 1 antibody, Ribosomal protein S6 kinase alpha-1 antibody, Ribosomal protein S6 kinase polypeptide 1 antibody, Ribosomal S6 kinase 1 antibody, RPS6K1 alpha antibody, rps6ka antibody, Rps6ka1 antibody, RSK 1 antibody, RSK 1 p90 antibody, RSK antibody, RSK-1 antibody, RSK1 antibody, RSK1p90 antibody, S6K alpha 1 antibody, S6K-alpha-1 antibody
- UniProt
- Q15418
- 途径
- MAPK Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades
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