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LIM Domain Kinase 1 抗体 (pThr508)

LIMK1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7138862
发货至: 中国
  • 抗原 See all LIM Domain Kinase 1 (LIMK1) 抗体
    LIM Domain Kinase 1 (LIMK1)
    抗原表位
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    pThr508
    适用
    • 106
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    • 2
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    宿主
    • 101
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    克隆类型
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    多克隆
    标记
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    This LIM Domain Kinase 1 antibody is un-conjugated
    应用范围
    • 89
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    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
    免疫原
    Peptide sequence around phosphorylation site of threonine 508 (R-Y-T(p)-V-V) derived from Human LIMK1.
    亚型
    IgG
    Top Product
    Discover our top product LIMK1 Primary Antibody
  • 应用备注
    WB:1:500-1:1000, IHC:1:50-1:100, IF:1:100-1:200,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    LIM Domain Kinase 1 (LIMK1)
    别名
    LIMK1 (LIMK1 产品)
    别名
    limk1 antibody, xlimk1 antibody, GB16654 antibody, LIMK1 antibody, LIMK antibody, LIMK-1 antibody, LIM domain kinase 1 antibody, LIM domain kinase 1a antibody, LIM domain kinase 1 L homeolog antibody, LIM-domain containing, protein kinase antibody, LIMK1 antibody, limk1a antibody, limk1 antibody, CpipJ_CPIJ000717 antibody, LOC413152 antibody, Limk1 antibody, limk1.L antibody
    背景

    Background: Protein kinase which regulates actin filament dynamics. Phosphorylates and inactivates the actin binding/depolymerizing factor cofilin, thereby stabilizing the actin cytoskeleton. Isoform 3 has a dominant negative effect on actin cytoskeletal changes. May be involved in brain development.

    Soosairajah J, et al. (2005) EMBO J.
    Ohashi K, et al. (2000) J Biol Chem, 275(5): 3577-82.
    Edwards DC, et al. (1999) Nat Cell Biol, 1(5): 253-9.

    Aliases: EC 2.7.11.1 antibody, LIM domain kinase 1 antibody, LIM motif-containing protein kinase antibody, LIMK antibody, LIMK-1 antibody, limk1 antibody, LIMK1_HUMAN antibody

    UniProt
    P53667
    途径
    Caspase Cascade in Apoptosis, Regulation of Cell Size, CXCR4-mediated Signaling Events
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