Cyclin H 抗体 (pThr315)
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- 抗原 See all Cyclin H (CCNH) 抗体
- Cyclin H (CCNH)
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抗原表位
- pThr315
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Cyclin H antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 交叉反应
- 人, 小鼠
- 纯化方法
- Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
- 免疫原
- Peptide sequence around phosphorylation site of threonine 315 (E-W-T(p)-D-D) derived from Human Cyclin H .
- 亚型
- IgG
- Top Product
- Discover our top product CCNH Primary Antibody
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- 应用备注
- WB:1:500-1:1000,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- Cyclin H (CCNH)
- 别名
- CCNH (CCNH 产品)
- 别名
- zgc:114132 antibody, cak antibody, p34 antibody, p37 antibody, Cych antibody, ACYPI004637 antibody, ccnh antibody, Cyclin-H antibody, 142767_at antibody, CG7405 antibody, Dmel\\CG7405 antibody, CAK antibody, 6330408H09Rik antibody, AI661354 antibody, AV102684 antibody, AW538719 antibody, ccnh-A antibody, cyclin H antibody, cyclin-H antibody, Cyclin H antibody, CYclin H antibody, cyclin H L homeolog antibody, CCNH antibody, ccnh antibody, LOC5577539 antibody, Cych antibody, CycH antibody, cyh-1 antibody, Ccnh antibody, ccnh.L antibody
- 背景
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Background:
Regulates CDK7, the catalytic subunit of the CDK-activating kinase (CAK) enzymatic complex. CAK activates the cyclin-associated kinases CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive C-terminal domain (CTD) of its large subunit (POLR2A), allowing its escape from the promoter and elongation of the transcripts. Involved in cell cycle control and in RNA transcription by RNA polymerase II. Its expression and activity are constant throughout the cell cycle.
Maekelae T.P., Nature 371:254-257(1994).
Fisher R.P., Cell 78:713-724(1994).
The MGC Project Team, Genome Res. 14:2121-2127(2004).Aliases: 6330408H09Rik antibody, AI661354 antibody, AV102684 antibody, AW538719 antibody, CAK antibody, CAK complex subunit antibody, ccnh antibody, CCNH_HUMAN antibody, CDK activating kinase antibody, CDK activating kinase complex subunit antibody, Cyclin dependent kinase activating kinase antibody, cyclin dependent kinase activating kinase complex subunit antibody, Cyclin H antibody, Cyclin-H antibody, CyclinH antibody, MO15 associated protein antibody, MO15-associated protein antibody, p34 antibody, p36 antibody, p37 antibody
- UniProt
- P51946
- 途径
- Cell Division Cycle, Mitotic G1-G1/S Phases, M Phase
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