Aurora A 抗体 (pThr288)
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- 抗原 See all Aurora A (AURKA) 抗体
- Aurora A (AURKA) (Aurora Kinase A (AURKA))
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抗原表位
- pThr288
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Aurora A antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- 交叉反应
- 人, 小鼠
- 纯化方法
- Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
- 免疫原
- Peptide sequence around phosphorylation site of threonine 288 (R-T-T(p)-L-M) derived from Human Aurora A.
- 亚型
- IgG
- Top Product
- Discover our top product AURKA Primary Antibody
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- 应用备注
- WB:1:500-1:1000, IHC:1:50-1:100,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- Aurora A (AURKA) (Aurora Kinase A (AURKA))
- 别名
- AURKA (AURKA 产品)
- 别名
- AIK antibody, ARK1 antibody, AURA antibody, AURORA2 antibody, BTAK antibody, PPP1R47 antibody, STK15 antibody, STK6 antibody, STK7 antibody, AIRK1 antibody, AU019385 antibody, AW539821 antibody, Ark1 antibody, Aurora-A antibody, Ayk1 antibody, IAK antibody, IAK1 antibody, Stk6 antibody, 87A7-9/2 antibody, Aur-A antibody, AurA antibody, CG3068 antibody, Dmel\\CG3068 antibody, aur-A antibody, aurA antibody, ck10 antibody, ck[10] antibody, l(3)87Ac antibody, l(3)ck10 antibody, ARK-1 antibody, Eg2 antibody, aik antibody, ark1 antibody, aur-a antibody, aura antibody, aurka-a antibody, aurora2 antibody, btak antibody, stk15 antibody, stk6 antibody, stk7 antibody, pEg2 antibody, wu:fb37c10 antibody, wu:fc02c02 antibody, zgc:100912 antibody, AURKA antibody, aurka antibody, aurora kinase A antibody, aurora A antibody, aurora kinase A L homeolog antibody, hypothetical protein antibody, aurora kinase A S homeolog antibody, AURKA antibody, Aurka antibody, aurA antibody, aurka.L antibody, aurka antibody, Aurora-A antibody, aurka.S antibody
- 背景
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Background:
Contributes to the regulation of cell cycle progression. Required for normal mitosis. Associates with the centrosome and the spindle microtubules during mitosis and functions in centrosome maturation, spindle assembly, maintenance of spindle bipolarity, centrosome separation and mitotic checkpoint control. Phosphorylates numerous target proteins, including ARHGEF2, BRCA1, KIF2A, NDEL1, PARD3, PLK1 and BORA. Regulates KIF2A tubulin depolymerase activity By similarity. Required for normal axon formation. Plays a role in microtubule remodeling during neurite extension. Important for microtubule formation and/or stabilization.
Bischoff, J.R. et al. (1998) EMBO J 17, 3052-65.
Hauf, S. et al. (2003) J Cell Biol 161, 281-94.
Walter, A.O. et al. (2000) Oncogene 19, 4906-16.
Zhou, H. et al. (1998) Nat Genet 20, 189-93.Aliases: AIK antibody, ARK-1 antibody, ARK1 antibody, AURA antibody, Aurka antibody, Aurora 2 antibody, Aurora A antibody, Aurora kinase A antibody, Aurora-related kinase 1 antibody, Aurora/IPL1 like kinase antibody, AURORA/IPL1-like kinase antibody, Aurora/IPL1-related kinase 1 antibody, AURORA2 antibody, Breast tumor-amplified kinase antibody, BTAK antibody, hARK1 antibody, IAK antibody, IPL1 related kinase antibody, MGC34538 antibody, OTTHUMP00000031340 antibody, OTTHUMP00000031341 antibody, OTTHUMP00000031342 antibody, OTTHUMP00000031343 antibody, OTTHUMP00000031344 antibody, OTTHUMP00000031345 antibody, OTTHUMP00000166071 antibody, OTTHUMP00000166072 antibody, PPP1R47 antibody, Protein phosphatase 1, regulatory subunit 47 antibody, Serine/threonine kinase 15 antibody, Serine/threonine kinase 6 antibody, Serine/threonine protein kinase 15 antibody, Serine/threonine-protein kinase 15 antibody, Serine/threonine-protein kinase 6 antibody, Serine/threonine-protein kinase aurora-A antibody, STK15 antibody, STK6 antibody, STK6_HUMAN antibody, STK7 antibody
- UniProt
- O14965
- 途径
- Cell Division Cycle, Asymmetric Protein Localization
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